Enhancing the Properties of Ti6Al4V as a Biomedical Material: A Review

Abstract

Abstract:The alloy Ti 6 Al 4 V has evolved as a good biomedical material, by virtue of its bio-compatibility. In order to make implants out of this material, it has to be shaped and processed. Shaping this material by conventional manufacturing methods like machining, welding and brazing presents a huge challenge. This challenge has been met by various approaches like additive manufacturing, surface alloying and heat treatment. Additive manufacturing processes are used for shaping; coatings and surface alloying are used for property improvement; heat treatment is used for improving the machinability. The processing method has an impact on the final properties of the product. This review attempts to trace the development of methods and practices for converting Ti 6 Al 4 V into a useful material for biomedical applications.

Electroless Ni–B Coating of Pure Titanium Surface for Enhanced Tribocorrosion Performance in Artificial Saliva and Antibacterial Activity

“…However, the formation of a bacterial surface biofilm, compromised immunity at the implant/tissue interface and poor tribological performance may lead to persistent infections on and around corrosion resistant Ti biomaterials used in corrosive environments [1,2]. Thus, numerous strategies focusing on the surface modification of Ti alloys have been employed to render them protection from both wear, corrosion and even tribocorrosion [3][4][5]. The strategies include physical vapour deposition [6], thermal spray [6,7], ion or laser nitriding [8][9][10], thermal oxidation [11,12], micro-arc oxidation [13][14][15], diffusion [16] and anodic oxidation treatments [17].…”

Biocompatibility of a Ti-Rich Medium-Entropy Alloy with Glioblastoma Astrocytoma Cells

“…Titanium (Ti) alloys with high specific strength and high corrosion resistance are excellent candidates for use in biomedical applications involving implantation [ 1 ]. Ti-6Al-4V ELI (TC4 ELI) is used in various fields, including as a biomedical material [ 2 ]. However, it suffers from poor mechanical strength, high elastic modulus, and bio-toxicity [ 3 , 4 ].…”

Implantation of heat treatment Ti6al4v alloys in femoral bone of Wistar rats

“…Biocompatibility is also affected by microstructural changes because the chemical composition of the passive oxide formed on the metal surface is different affecting cell adhesion, biocompatibility, and, consequently, osseointegration [4,[27][28][29]. Some studies on the performance of Ti and titanium alloys against real biological environments have been carried out through in vivo tests with experimental animals [30][31][32][33][34][35]. Among these works, it has been reported that there is no bone formation after 30 days of implantation of Ti6Al4V heattreated alloys in femurs rats [34].…”