Enhancing the sensitivity and selectivity of salbutamol detection using reduced graphene oxide combined with molecularly imprinted polymers (RGO/MIP)

Abstract

In this study, to enhance selective and sensitive salbutamol detection based on the carbon plate electrode was modified with the novel-molecularly imprinted polymer (MIP) combined with reduced graphene oxide (RGO). RGO/MIP was prepared by polymerization containing methacrylic acid as a monomer and salbutamol as a template. The modified electrode was observed surface morphology by FE-SEM, tested performance by an electrochemical technique which was investigated both cyclic voltammetry (CV) and amperometry (AMP) mode. The performance of the modified electrode was compared between MIP and RGO/MIP electrode, which the RGO/MIP electrode was demonstrated at 4.16 nA/ppm of sensitivity higher than 0.91 nA/ppm of MIP electrode. There was a limit of detection (LOD) of the RGO/MIP electrode at 0.83 ppm lower than the MIP electrode. Moreover, RGO/MIP electrode was dynamic ranges from 1 to 1000 ppm, exhibited stability, repeatability, fast response, and high selectivity for salbutamol detection.

Enhancement in Sensitivity and Selectivity of Electrochemical Technique with CuO/g-C3N4 Nanocomposite Combined with Molecularly Imprinted Polymer for Melamine Detection

“…They are easily synthesized, cost-effective, and resistant to fluctuations in temperature and pH [43][44][45]. The molecular imprinting technique has recently gained considerable attention due to its wide range of applications, such as food allergy detection [46][47][48], drug delivery [49], medicinal applications [50], biosensors [51], pesticides [52,53], and others.…”

Preparation of surface-modified electrode of copper(ii) oxide mixed with the molecularly imprinted polymer for enhancement of melamine detection with photoelectrochemical technique

“…The specic cavities formed in the MIP are compatible with the target analyte in terms of size, shape, and chemical function. [21][22][23] Therefore, MIPs are widely used in sensors for recognition of analytes such as pesticides, organic compounds, and biomolecules 21,22,[24][25][26][27][28][29] because of their high selectivity, robust thermal and chemical stability, long storage time, ease of preparation, and low cost. However, MIPs are polymer matrices with low electrical conductivity; when an MIP is modied onto the surface of an electrode, it hampers charge transfer between the solution and electrode.…”