Enhancing uric acid electrochemical detection with copper ion-activated mini protein mimicking uricase within ZIF-8: response surface methodology (RSM) optimization

Abdul Aziz, Siti Fatimah Nur; Hui, Ong Sin; Salleh, Abu Bakar; Normi, Yahaya M.; Yusof, Nor Azah; Ashari, Siti Efliza; Alang Ahmad, Shahrul Ainliah

doi:10.1007/s00216-023-05011-z

Anal Bioanal Chem

2023

DOI: 10.1007/s00216-023-05011-z

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Enhancing uric acid electrochemical detection with copper ion-activated mini protein mimicking uricase within ZIF-8: response surface methodology (RSM) optimization

Siti Fatimah Nur Abdul Aziz,

Ong Sin Hui,

Abu Bakar Salleh

et al.

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2024

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Cited by 2 publications

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Bioinspired mp20 mimicking uricase in ZIF-8: Metal ion dependent for controllable activity

Abdul Aziz,

Salleh,

Normi

et al. 2024

Enzyme and Microbial Technology

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Bioinspired mp20 mimicking uricase in ZIF-8: Metal ion dependent for controllable activity

Abdul Aziz,

Salleh,

Normi

et al. 2024

Enzyme and Microbial Technology

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Auriferous nanozymes: advances in diagnostic and therapeutic applications

Deshwal,

Tripathi,

Saxena

et al. 2024

Nanotechnology

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Nanozymes are a group of nanomaterials that garnered significant attention due to their enzyme-mimicking properties and their catalytic activities comparable to those of natural enzymes. The ability of nanozymes to emulate crucial biological processes which can conquer the drawbacks of natural enzymes, such as their restricted thermostability as well as substrate range. Auriferous (gold) nanozymes possess remarkable enzyme-like properties, such as reductase, peroxidase, superoxide dismutase, oxidase, and catalase. This characteristic makes them a strong competitor for possible applications in the fields of biomedicine as well as biochemical analysis, especially when compared to natural enzymes, along with their simple manufacturing, adaptable features, biocompatibility, and affordability. This review evaluates the factors that affect the catalytic activity of auriferous nanozymes. We offer a thorough investigation of their diagnostic applications, including detecting cancer, microorganisms, glucose, cysteine, and uric acid. Furthermore, we delve into the applications of gold nanozyme in therapeutics including chemodynamic therapy, radiotherapy, and photothermal therapy. In contrast to previous research, our review highlights various advantages of auriferous nanozymes in diagnostics and therapies and provides novel insights into the diverse applications of gold nanozymes encompassing current research studies.

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Enhancing uric acid electrochemical detection with copper ion-activated mini protein mimicking uricase within ZIF-8: response surface methodology (RSM) optimization

Cited by 2 publications

References 50 publications

Bioinspired mp20 mimicking uricase in ZIF-8: Metal ion dependent for controllable activity

Bioinspired mp20 mimicking uricase in ZIF-8: Metal ion dependent for controllable activity

Auriferous nanozymes: advances in diagnostic and therapeutic applications

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