Enlargement of sacral subcutaneous meningocele associated with retained medullary cord

Shirozu, Noritoshi; Morioka, Takato; Inoha, Satoshi; Imamoto, Naoyuki; Sasaguri, Toshiyuki

doi:10.1007/s00381-018-3812-z

Cited by 18 publications

(22 citation statements)

References 13 publications

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“…Morphologically, there was a striking resemblance between the ependyma-lined canal with surrounding neuroglial tissues in our 6 patients with filar- and caudal-type lipomatous malformations and the RMC of the previous reports [8, 9], including ours [10, 11]. Furthermore, the cases were also similar to these previous cases in that there were always neuroglial tissues surrounded by variable amounts of collagenous and adipose tissues [8-11].…”

Section: Discussionsupporting

confidence: 72%

“…Furthermore, the cases were also similar to these previous cases in that there were always neuroglial tissues surrounded by variable amounts of collagenous and adipose tissues [8-11]. The only difference was the amount of adipose tissues; it was apparently greater in the lipomatous malformation than in RMC.…”

Section: Discussionsupporting

confidence: 68%

“…In these cases, intraoperative stimulation indicated that this cord was a “redundant” nonfunctional cord below the true conus [8-11]. Pang et al [8] proposed that these cords are portions of the medullary cord and normally regress but can remain because of late arrest of secondary neurulation before the degenerative phase.…”

Section: Introductionmentioning

confidence: 99%

“…Pang et al [8] proposed that these cords are portions of the medullary cord and normally regress but can remain because of late arrest of secondary neurulation before the degenerative phase. The central feature in the histopathology of RMC is an ependyma-lined central canal in the dense neuroglial core [8-11]. …”

Section: Introductionmentioning

confidence: 99%

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Ependyma-Lined Canal with Surrounding Neuroglial Tissues in Lumbosacral Lipomatous Malformations: Relationship with Retained Medullary Cord

et al. 2018

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Background: An ependyma-lined canal with surrounding neuroglial tissues can be present in lumbosacral lipomatous malformations; however, the precise embryological significance is still unclear. Method: Six out of 50 patients with lipomatous malformations had ependymal structures. We retrospectively analyzed the clinical, neuroradiological, and histological findings of these patients to demonstrate the relationship with the embryological background of the retained medullary cord (RMC), which normally regresses, but was retained here because of late arrest of secondary neurulation. Results: Five (13.9%) of 36 patients with filar and caudal types and 1 of 3 lipomyelomeningoceles had ependymal structures, while none with dorsal and transitional types had these tissues. Histologically, the ependymal structures surrounded by neuroglial tissue and containing various amounts of adipose tissue bear a striking resemblance to the ependymal structures in RMC. Conclusion: The 13.9% incidence of association between the ependymal structures and filar and caudal types is thought to be because of second ary neurulation failure with the same embryological background as that of RMC. Dorsal and transitional types, resulting from primary neurulation failure, therefore, did not have ependymal structures.

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Section: Discussionsupporting

confidence: 72%

Section: Discussionsupporting

confidence: 68%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Ependyma-Lined Canal with Surrounding Neuroglial Tissues in Lumbosacral Lipomatous Malformations: Relationship with Retained Medullary Cord

et al. 2018

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“…An RMC can, by default, be accompanied by other secondary neurulation anomalies such as presacral cysts or sacral agenesis. In the literature, caudal lipomas, limited dorsal myeloschisis, congenital dermal sinuses, subcutaneous meningoceles, and split cord malformations can be associated with RMCs 8,11,16,19) .…”

Section: Neuroimagingmentioning

confidence: 99%

Secondary Neurulation Defects-1 : Retained Medullary Cord

Kim

Lee

Wang

2020

J Korean Neurosurg Soc

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Retained medullary cord (RMC) is a relatively recent term. Pang et al. newly defined the RMC as a late arrest of secondary neurulation leaving a non-functional vestigial portion at the tip of the conus medullaris. RMC, which belongs to the category of closed spinal dysraphism, is a cord-like structure that is elongated from the conus toward the cul-de-sac. Because intraoperative electrophysiological confirmation of a non-functional conus is essential for the diagnosis of RMC, only a tentative or an assumptive diagnosis is possible before surgery or in cases of limited surgical exposure. We suggest the term 'possible RMC' for these cases. An RMC may cause tethered cord syndrome and thus requires surgery. This article reviews the literature to elucidate the pathoembryogenesis, clinical significance and treatment of RMCs.

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Secondary Neurulation Defects: Retained Medullary Cord

Kim,

Lee,

Wang

2023

Advances and Technical Standards in Neurosurgery

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Enlargement of sacral subcutaneous meningocele associated with retained medullary cord

Abstract: It is conceivable that the hydrodynamic pressure with standing position and the check valve phenomenon were involved in meningocele enlargement. We should be mindful of these potential morphological changes.

Cited by 18 publications

References 13 publications

Ependyma-Lined Canal with Surrounding Neuroglial Tissues in Lumbosacral Lipomatous Malformations: Relationship with Retained Medullary Cord

Ependyma-Lined Canal with Surrounding Neuroglial Tissues in Lumbosacral Lipomatous Malformations: Relationship with Retained Medullary Cord

Secondary Neurulation Defects-1 : Retained Medullary Cord

Secondary Neurulation Defects: Retained Medullary Cord

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