With the integration of technology into learning environments, traditional learning approaches have begun to leave their place to current learning approaches. One of the current learning approaches that has been popularly used recently is blended learning. Because of the various advantages it provides, blended learning is preferred by learners, teachers, and educational institutions. With the current COVID-19 pandemic, higher education institutions' interest in blended learning has increased. This growing interest raises the issue of how efficient blended learning should be. In this context, researchers investigated the requirements of effective blended learning for higher education institutions in this chapter. In the chapter, the researchers also discuss the contents of blended learning models that can be used in higher education, current research, blended learning adoption process in higher education, and tips for effective blended learning.