Enrichment, analysis, identification and mechanism of antioxidant components in Toona sinensis

Wang, Yunxiao; Gu, Dongyu; Liu, Chang; Tang, Shanshan; Wang, Shuai; Wang, Yi; Yang, Yi

doi:10.1016/j.cjac.2022.100198

Cited by 9 publications

(4 citation statements)

References 35 publications

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“…1,2,3,4,6-Penta-O-galloyl-β-D-glucose (167) and ethyl gallate (156) were obtained from the young leaves of T. sinensis by establishing a liquid-liquid refined extraction-guided bioassay. The EC 50 (the concentration for 50% of maximal effect) values of ethyl gallate (156) scavenging ABTS and DPPH were 4.46 ± 0.05 and 7.61 ± 0.13 µg/mL, respectively, and those of 1,2,3,4,6-penta-O-galloyl-β-D-glucose (167) scavenging ABTS and DPPH were 12.90 ± 0.16 and 16.29 ± 0.20 µg/mL, respectively, indicating that they were good antioxidants [68]. Four chemical-induced oxidative models were applied in the previous study, including DPPH free-radical scavenging assay, phenazine methosulphate (PMS) nicotinamide adenine dinucleotide (NADH) PMS-NADH-NBT superoxide anion scavenging assay, FeCl 3 -K 3 Fe (CN) 6 reducing power assay and FeCl 2 -FerroZine metal chelation assay.…”

Section: Antioxidant Activitymentioning

confidence: 99%

Traditional Uses, Chemical Constituents and Pharmacological Activities of the Toona sinensis Plant

Zhao,

Li,

Wang

et al. 2024

Molecules

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Toona sinensis (A. Juss.) Roem., which is widely distributed in China, is a homologous plant resource of medicine and food. The leaves, seeds, barks, buds and pericarps of T. sinensis can be used as medicine with traditional efficacy. Due to its extensive use in traditional medicine in the ancient world, the T. sinensis plant has significant development potential. In this review, 206 compounds, including triterpenoids (1–133), sesquiterpenoids (134–135), diterpenoids (136–142), sterols (143–147), phenols (148–167), flavonoids (168–186), phenylpropanoids (187–192) and others (193–206), are isolated from the T. sinensis plant. The mass spectrum cracking laws of representative compounds (64, 128, 129, 154–156, 175, 177, 179 and 183) are reviewed, which are conducive to the discovery of novel active substances. Modern pharmacological studies have shown that T. sinensis extracts and their compounds have antidiabetic, antidiabetic nephropathy, antioxidant, anti-inflammatory, antitumor, hepatoprotective, antiviral, antibacterial, immunopotentiation and other biological activities. The traditional uses, chemical constituents, compound cracking laws and pharmacological activities of different parts of T. sinensis are reviewed, laying the foundation for improving the development and utilization of its medicinal value.

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Section: Antioxidant Activitymentioning

confidence: 99%

Traditional Uses, Chemical Constituents and Pharmacological Activities of the Toona sinensis Plant

Zhao,

Li,

Wang

et al. 2024

Molecules

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“…To apply it, the leaves are crushed and applied to the affected itchy skin. Furthermore, other parts of the tree, including the stem, bark, roots, and fruits, are commonly employed for the treatment of various ailments [ 36 , 82 ]. Many SAD people use surian stems as building material to make pillars for their houses, the bark is used as a diarrhea medicine and astringent, the roots are used as a detoxifier while the fruit is used to treat eye infections.…”

Section: Herbs With Anti-aging Propertiesmentioning

confidence: 99%

“…Toona sinensis is extensively utilized in Traditional Chinese Medicine (TCM), and its various parts, including the leaves, stems, bark, roots, and fruits, have been employed for treating a wide range of ailments. Traditionally, the stems and leaves of this plant are used for addressing conditions such as dysentery, enteritis, carminative effects, and skin disorders such as itching [ 82 ]. Furthermore, the roots are used as curatives, the bark is used as an astringent and depurative, and the fruits are utilized as an astringent for treating eye infections [ 36 ].…”

Section: Herbs With Anti-aging Propertiesmentioning

confidence: 99%

Anti-Aging Potential of Plants of the Anak Dalam Tribe, Jambi, Indonesia

Lestari,

Muhaimin,

Chaerunisaa

et al. 2023

Pharmaceuticals

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The process of skin aging is a physiological phenomenon that can not be avoided. According to global population data, the rate of aging increases by approximately 13% every year. The impact of skin aging has become a significant concern and challenge for developed countries. Consequently, there has been a search for potential new anti-aging agents. This review aims to provide an overview of the current research status of plants of the Anak Dalam Tribe (Indonesian: Suku Anak Dalam [SAD]; referred to as SAD henceforth) in Jambi Province, Indonesia, for the development of potential new anti-aging agents. One such discovery is a product derived from natural ingredients with the ability to prevent premature aging. These new anti-aging plants have been used for centuries by the Anak Dalam tribe, for treating skin diseases and maintaining skin health through traditional remedies. Recent research on herbal formulations used by the SAD community in Indonesia for skin beauty treatments, reported by Research on Medicinal Plants and Herbs or RISTOJA, indicates that 64 plant species are used for skin care. Among these plants, Toona sinensis, Curcuma heyneana, Curcuma zedoaria, Curcuma longa, and Kaempferia rotunda are the most commonly used medicinal plants with anti-aging properties. T. sinensis is a tree, while the others are herbs. T. sinensis shows the highest potential for development as an anti-aging agent, with its extracts, active fractions, and bioactive quercetin isolates known to possess strong anti-aging activities both in vitro and in vivo. Furthermore, C. heyneana, C. longa, C. zedoaria, and K. rotunda also show potential for further research, and three of them have demonstrated good potential for in vivo anti-aging activities. Only K. rotunda demonstrates relatively weaker antioxidant activity compared to T. sinensis, C. heyneana, C. longa, and C. zedoaria. Nevertheless, K. rotunda can still be developed to search for potential opportunities as agents with other activities, while T. sinensis, C. heyneana, C. longa, and C. zedoaria in the findings could be an opportunity to explore the potential of new anti-aging agents. In conclusion, of the five medicinal plants traditionally used by the SAD in Jambi, Indonesia, C. longa has received the most extensive research and shows potential for the development of anti-aging solutions. C. zedoaria, C. heyneana and K. rotunda show good potential for in vivo anti-aging activity. T. sinensis is the least-studied medicinal plant. Nevertheless, it has potential for development, as it is widely used by the SAD community for both traditional medicine and skin care.

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“…This plant is widely utilized in traditional medicine for various purposes, such as treating skin conditions, deworming, dysentery, expectorants, tonics, blood sugar reduction, and syphilis treatment [9]. Secondary metabolites present in this plant encompass limonoids, phytol, flavonoids, essential oils, triterpenoids, phenols, and catechins [10,11]. These compounds are capable of countering various pathological conditions in the body that are mediated by oxidative stress, which is related to the aging and inflammation processes [12].…”

Section: Introductionmentioning

confidence: 99%

Antioxidant Activities and Phytochemical Screening of Ethanol Extract From Surian Leaves (Toona Sinensis)

LESTARI,

MUHAIMIN,

CHAERUNISAA

et al. 2023

Int J App Pharm

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Objective: The objective of the present study is to determine antioxidant activities and phytochemical screening of ethanol extract from surian leaves (Toona sinensis). Methods: This study evaluated the antioxidant activity and conducted phytochemical screening of ethanol extracts obtained from surian leaves. Phytochemical screening was performed using qualitative Thin-Layer Chromatography (TLC), and antioxidant activity was assessed using the DPPH method. Results: The results revealed the presence of polyphenolic compounds (153.10±0.310 mg/g), tannins, flavonoids (33.19±0.890 mg/g), monoterpenoids, quinones, and saponins with Rf values of 0.607±0.019 (flavonoids) and 0.958±0.019 (terpenoids) 0.513±0.038 (steroids) 0.418±0.019 (phenolics). The antioxidant activity test of the ethanol extract from Surian leaves yielded an IC50 value of 12.351±0.092 ppm, which closely matches the IC50 value of the reference vitamin C (7.805±0.686 ppm). Conclusion: In conclusion, based on research methods, the ethanol extract of surian leaves contains flavonoid and phenolic compounds which show strong antioxidant activity.

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Enrichment, analysis, identification and mechanism of antioxidant components in Toona sinensis

Cited by 9 publications

References 35 publications

Traditional Uses, Chemical Constituents and Pharmacological Activities of the Toona sinensis Plant

Traditional Uses, Chemical Constituents and Pharmacological Activities of the Toona sinensis Plant

Anti-Aging Potential of Plants of the Anak Dalam Tribe, Jambi, Indonesia

Antioxidant Activities and Phytochemical Screening of Ethanol Extract From Surian Leaves (Toona Sinensis)

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