Enrichment of rosmarinic acid from comfrey (Symphytum officinale L.) root extract by macroporous adsorption resins and molecular docking studies

Alizadeh, Paria; Alizadeh, Pooneh; Rahimi, Masoud; Amjadi, Sajed; Bayati, Mohammad; Nejad Ebrahimi, Samad

doi:10.1016/j.indcrop.2024.118541

Industrial Crops and Products

2024

DOI: 10.1016/j.indcrop.2024.118541

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Enrichment of rosmarinic acid from comfrey (Symphytum officinale L.) root extract by macroporous adsorption resins and molecular docking studies

Paria Alizadeh,

Pooneh Alizadeh,

Masoud Rahimi

et al.

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2024

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Purification of Phenylethanoid Glycosides From Syringa pubescens Turcz. via Macroporous Resins and Comparison of Biological Activity

Zhang,

Wu,

Xiong

et al. 2024

Separation Science Plus

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Syringa pubescens Turcz. has been universally employed to make flower tea for the treatment of cough in the western part of Henan Province. Many researchers have confirmed that the phenylethanoid glycosides from S. pubescens were bioactive compounds. In this study, various macroporous resins have been employed to evaluate the potential of adsorption and desorption for phenylethanoid glycosides. The HPD‐450 resins were appropriate for the purification of phenylethanoid glycosides, and the optimum purification conditions were established. The adsorption properties were well modeled using the pseudo‐second‐order kinetics. Meanwhile, the adsorption isotherm could be better represented by the Langmuir equation, suggesting that the process was an exothermic reaction. Moreover, the purified sample possessed a stronger antioxidant capacity. The inhibitory activity of the crude extract against α‐amylase and α‐glucosidase was stronger than that of purified sample. The findings obtained provided a scientific foundation for further research and high‐value exploration of this plant and a potential technique for scale‐up purification of phenylethanoid glycosides.

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Purification of Phenylethanoid Glycosides From Syringa pubescens Turcz. via Macroporous Resins and Comparison of Biological Activity

Zhang,

Wu,

Xiong

et al. 2024

Separation Science Plus

View full text Add to dashboard Cite

show abstract

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Enrichment of rosmarinic acid from comfrey (Symphytum officinale L.) root extract by macroporous adsorption resins and molecular docking studies

Cited by 1 publication

References 31 publications

Purification of Phenylethanoid Glycosides From Syringa pubescens Turcz. via Macroporous Resins and Comparison of Biological Activity

Purification of Phenylethanoid Glycosides From Syringa pubescens Turcz. via Macroporous Resins and Comparison of Biological Activity

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