This study addresses the critical challenge of accurately classifying brain tumors using artificial intelligence. Early detection is crucial, as untreated tumors can be fatal. Despite advances in AI, accurately classifying tumors remains a challenging task. To address this challenge, we propose a novel optimization approach called PSCS combined with deep learning for brain tumor classification. PSCS optimizes the classification process by improving Particle Swarm Optimization (PSO) exploitation using Cuckoo search (CS) algorithm. Next, classified gene expression data of brain tumor using Deep Learning (DL) to identify different groups or classes related to a particular tumor along with the PSCS optimization technique. The proposed optimization technique with DL achieves much better classification accuracy than other existing DL and Machine learning models with the different evaluation matrices such as Recall, Precision, F1‐Score, and confusion matrix. This research contributes to AI‐driven brain tumor diagnosis and classification, offering a promising solution for improved patient outcomes.