Enteral Nutrition by Alimentation Jejunostomy in 11 Cases of Severe Acute Pancreatitis

Maillet, P

doi:10.1007/978-3-642-68518-7_67

Cited by 3 publications

(3 citation statements)

References 9 publications

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“…At least eight studies are reported in the literature in which the infusion of enteral nutrients into the jejunum were used as transition feeding in pancreatitis patients in whom the inflammation had clearly peaked and begun to subside. [14][15][16][17][18][19][20][21] In our study, there was concern that even if jejunal feedings did cause some pancreatic stimulation, that an adverse clinical response might not be evident simply because the patients had only a mild degree of predominantly alcoholic pancreatitis. Anecdotal experience in the three TEN patients who failed to tolerate advancement to diet by mouth and the one TEN patient in whom the jejunal tube became displaced into the stomach provided reassurance against such concern.…”

Section: Methodsmentioning

confidence: 99%

“…[10][11][12][13] Case series have documented that TEN could be used safely as transitional feeding in patients who had peaked and had begun to resolve the inflammatory response associated with pancreatitis. [14][15][16][17][18][19][20][21] The potential advantages of TEN over TPN and the feasibility that TEN administered via jejunal feedings might be well tolerated prompted us to set up this prospective randomized trial comparing early TEN to TPN in acute pancreatitis. The objectives of this study were to determine the safety of TEN in a setting of acute pancreatic inflammation and to determine any benefit of TEN over TPN with regard to cost, efficacy, and impact on patient outcome in pancreatitis patients.…”

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confidence: 99%

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Comparison of the Safety of Early Enteral vs Parenteral Nutrition in Mild Acute Pancreatitis

McClave

Greene

Snider

et al. 1997

J Parenter Enteral Nutr

399

215

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Section: Methodsmentioning

confidence: 99%

mentioning

confidence: 99%

Comparison of the Safety of Early Enteral vs Parenteral Nutrition in Mild Acute Pancreatitis

McClave

Greene

Snider

et al. 1997

J Parenter Enteral Nutr

399

215

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“…In particular, there is an increased risk of central catheter infection, severe hyperglycaemia, and other metabolic and electrolyte disturbances and a possible exacerbation of metabolic disturbances. TPN may also result in gut barrier function alterations due to increasing intestinal permeability [1][2][3][4][5][6][7][8][9][10] . Benefits from the use of total enteral nutrition (TEN) have been noted in a number of other diseases, such as burns, trauma, and sepsis.…”

Section: Introductionmentioning

confidence: 99%

Parenteral versus early intrajejunal nutrition: Effect on pancreatitic natural course, entero-hormones release and its efficacy on dogs with acute pancreatitis

Qin

Su²,

Hu³

et al. 2003

WJG

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AIM:To evaluate the effect of early intrajejunal nutrition (EIN) on the natural course, entero-hormone secretion and its efficacy on dogs with acute pancreatitis. METHODS:An acute pancreatitis model was induced by injecting 1 ml/kg of combined solution (2.5 % sodium taurocholate and 8 000-10 000 BAEE units trypsin/ml) into the pancreas via pancreatic duct. Fifteen dogs were divided into parenteral nutrition (PN) group and EIN group. Two groups were isonitrogenous and isocaloric. EIN was used at postoperative 24 h. Serum glucose, calcium, amylase and lysosomal enzymes were determined before and 1, 4, 7 d after acute pancreatitis was induced. All the dogs were injected 50 uCi RESULTS:There was no difference between two groups in the contents of serum calcium, amylase and lysosomal enzymes, 125 I-BSA index of pancreas/muscle and pancreas/ blood and PPS. The contents of CCK and gastrin in EIN were higher than those in PN group at 60 and 120 min (P<0.05). The content of SEC post-infusion of nutrition solution was higher than that of pre-infusion of nutrition solution in both groups, and only at 60 min SEC in EIN group was higher than that in PN group. The content of gastrin in EIN was higher than that in PN group at 120 and 180 min (P<0.05). CONCLUSION: EIN does not stimulate entero-hormone and pancreatic juice secretion, and enzyme-protein synthesis and release. EIN has no effect on the natural course of acute pancreatitis.Qin HL, Su ZD, Hu LG, Ding ZX, Lin QT. Parenteral versus early intrajejunal nutrition: Effect on pancreatitic natural course, entero-hormones release and its efficacy on dogs with acute pancreatitis.

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Nutritional support in acute pancreatitis

Choudhuri

Tandon

1988

J of Gastro and Hepatol

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Acute pancreatitis is a catabolic condition requiring adequate nutritional support to avoid severe nitrogen loss. Providing nutrition to the patients with acute pancreatitis is, however, limited by the fact that oral feeding may stimulate the pancreas and aggravate the pancreatitis. Hence, total parenteral nutrition (TPN) is recommended for such patients but that too has limitations apart from its prohibitive cost. At the same time, therefore, enteral feeds have been developed, which provide adequate nutrition and are fairly well tolerated by these patients. Based on the available studies, a rational scheme of managing acute pancreatitis has been recommended. Patients with moderately severe acute pancreatitis who are malnourished or are likely to develop complications requiring surgery should be supported with total parenteral nutrition from an early stage. All patients with severe acute pancreatitis should, on the other hand, be supported with total parenteral nutrition from the beginning, but enteral nutrition via a jejunostomy should be commenced as early as possible since such patients often run a protracted course and giving them T P N might become exorbitantly expensive and impractical. Mixed or polymeric feeds are tolerated well from the sixth or seventh postoperative day but in an occasional patient elemental diet via the jejunostomy may become necessary.

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Enteral Nutrition by Alimentation Jejunostomy in 11 Cases of Severe Acute Pancreatitis

Cited by 3 publications

References 9 publications

Comparison of the Safety of Early Enteral vs Parenteral Nutrition in Mild Acute Pancreatitis

Comparison of the Safety of Early Enteral vs Parenteral Nutrition in Mild Acute Pancreatitis

Parenteral versus early intrajejunal nutrition: Effect on pancreatitic natural course, entero-hormones release and its efficacy on dogs with acute pancreatitis

Nutritional support in acute pancreatitis

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