Enteral versus parenteral nutrition for acute pancreatitis

Al‐Omran, Mohammed; Groof, Ala; Wilke, Derek

doi:10.1002/14651858.cd002837

Cited by 78 publications

(60 citation statements)

References 30 publications

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“…The conclusions of the two meta-analyses, one of which reported on six studies (181) and the other on two of the six studies (180), were contradictory. In one, enteral nutrition was favored versus TPN (180); in the other, the interpretation was that there were insufficient data to provide firm conclusions about the safety and efficacy of enteral nutrition when compared to TPN (181).…”

Section: Level Of Evidence: IImentioning

confidence: 98%

“…All have included relatively few patients (median 33, range 17-53) that have differed considerably in entry criteria. There have been other methodologic concerns that have been well outlined in two meta-analyses (180,181). In general, it is reasonable to conclude that enteral feeding is safer and less expensive than TPN, but there is not yet convincing findings that there are major improvements in morbidity and mortality of acute pancreatitis.…”

Section: Level Of Evidence: IImentioning

confidence: 99%

See 1 more Smart Citation

Practice Guidelines in Acute Pancreatitis

Banks

Freeman

2006

Am J Gastroenterology

1,677

980

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Section: Level Of Evidence: IImentioning

confidence: 98%

Section: Level Of Evidence: IImentioning

confidence: 99%

Practice Guidelines in Acute Pancreatitis

Banks

Freeman

2006

Am J Gastroenterology

1,677

980

View full text Add to dashboard Cite

“…Li (1998) have proven that the function of rat intestinal barrier will be significantly weakened after TPN supportive treatment, and 100% bacteria translocation will occur if there is a hemorrhagic shock. The early enteral nutuition (EN) might be indispensable to the protection of intestinal mucosa barrier of rats (Al-Omran et al, 2003;Marik and Zaloga, 2004). Grady et al(2000) found that PAF played an important role in the progression of pancreatitis complicated with functional disturbance of intestinal mucosa barrier.…”

Section: Influence Of Enteral Nutrition Deficiency On Injury Of Intesmentioning

confidence: 99%

Mechanism of acute pancreatitis complicated with injury of intestinal mucosa barrier

Zhang

Song

et al. 2007

J. Zhejiang Univ. - Sci. B

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Acute pancreatitis (AP) is a common acute abdomen in clinic with a rapid onset and dangerous pathogenetic condition.AP can cause an injury of intestinal mucosa barrier, leading to translocation of bacteria or endotoxin through multiple routes, bacterial translocation (BT), gutorigin endotoxaemia, and secondary infection of pancreatic tissue, and then cause systemic inflammatory response syndrome (SIRS) or multiple organ dysfunction syndrome (MODS), which are important factors influencing AP's severity and mortality. Meanwhile, the injury of intestinal mucosa barrier plays a key role in AP's process. Therefore, it is clinically important to study the relationship between the injury of intestinal mucosa barrier and AP. In addition, many factors such as microcirculation disturbance, ischemical reperfusion injury, excessive release of inflammatory mediators and apoptosis may also play important roles in the damage of intestinal mucosa barrier. In this review, we summarize studies on mechanisms of AP.

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“…The diet should not necessarily be liquid or semi-liquid, but should be low-fat and low residue. 126,127 In severe cases, artificial feeding is necessary with endoscopic or radiological positioning of naso-jejunal tube (preferred) and enteral nutrition formulas rich in protein and low in fat (with a caloric need of 25 kcal/kg of ideal weight). This approach allows, with respect to the total parenteral nutrition (TPN), to maintain the integrity of the intestinal barrier, to reduce the risk of intestinal atrophy and bacterial/fungal translocation and to reduce the risk of sepsis related to the use of central venous access (CVC) and TPN.…”

Section: Nutritionmentioning

confidence: 99%

The management of the patient with acute pancreatitis: from evidence to clinical practice

Cenci

Restuccia

Gnerre³

et al. 2017

Ital J Med

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Acute pancreatitis is an inflammatory disorder of the pancreas characterized by abdominal pain and elevation of pancreatic enzymes in the blood. The pathogenesis is complex and partly unknown and the evolution is often unpredictable. Many efforts have been made to define this disease and its complications and to classify different grades of severity in order to formulate prognostic scores that could guide the physician in choosing the optimal therapeutic setting and procedures. The management of the patient with pancreatitis is not always optimal and differs among internist, gastroenterologist or surgeon. We think that a patient with clinical suspicion of acute pancreatitis is admitted to medical or surgical department depending on the availability of beds and not according to evidence-based medicine. The aim of this monograph is to identify the optimal management of patients with acute pancreatitis admitted to hospital.

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Enteral versus parenteral nutrition for acute pancreatitis

Cited by 78 publications

References 30 publications

Practice Guidelines in Acute Pancreatitis

Practice Guidelines in Acute Pancreatitis

Mechanism of acute pancreatitis complicated with injury of intestinal mucosa barrier

The management of the patient with acute pancreatitis: from evidence to clinical practice

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