2016
DOI: 10.1007/s10620-016-4183-5
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Enteric Nervous System: Neuropathic Gastrointestinal Motility

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Cited by 28 publications
(26 citation statements)
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“…The small intestine ENS is equipped to perform functions relating to inflammation, digestion, secretion and motility among others [67][68][69]. The identification of several neuronal terms for central genes in the small intestine network is in line with such literature findings ( Figs 10 and 11) [67][68][69].…”
Section: Randomization Experimentssupporting
confidence: 78%
See 1 more Smart Citation
“…The small intestine ENS is equipped to perform functions relating to inflammation, digestion, secretion and motility among others [67][68][69]. The identification of several neuronal terms for central genes in the small intestine network is in line with such literature findings ( Figs 10 and 11) [67][68][69].…”
Section: Randomization Experimentssupporting
confidence: 78%
“…These vitamins are essential for several biological processes and their enrichment in large intestine specific gene network only seems natural (Figs 10 and 11). The brain-in-the-gut or the enteric nervous system (ENS) is the largest component of the autonomous nervous system [67][68][69]. The small intestine ENS is equipped to perform functions relating to inflammation, digestion, secretion and motility among others [67][68][69].…”
Section: Randomization Experimentsmentioning
confidence: 99%
“… 2 Broad abnormalities in the brain–gut axis contribute to the pain component of FGIDs, 3 but it is clear that changes in gut motility are driven primarily by alterations to the enteric nervous system (ENS). 4 The ENS is a complex network of enteric neurons and glia embedded within the gut wall that provides local control over reflexive gut functions such as fluid exchange across the mucosa, local blood flow, and patterns of motility. 5 Inflammation can disrupt the control of these gastrointestinal (GI) reflexes by altering both the function and survival of enteric neurons that then contribute to the development of FGIDs.…”
mentioning
confidence: 99%
“…Nervous and humoral factors, more precisely neurotransmitters of the enteric nervous system, regulate the spontaneous rhythmic contraction and relaxation of smooth muscles of the intestine. The enteric nervous system (brain-in-the-gut) is essential for normal motility of the small intestine [21]. It is known that extracts which affect the contractility of the intestine, have neurophysiological activity [22,23].…”
Section: Discussionmentioning
confidence: 99%