Entrapment in HydrIL gels: Hydro-Ionic Liquid polymer gels for enzyme immobilization

Pérez-Tomás, José Ángel; Brucato, Rebekah; Griffin, Preston; Kostal, Jakub; Brown, Gareth; Mix, Stefan; Marr, Patricia C.; Marr, Andrew C.

doi:10.1016/j.cattod.2024.114595

Cited by 5 publications

(2 citation statements)

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“…However, there are various ways to fix enzyme problems. One of these methods is enzyme immobilization. , Porous substrate is one of the most widely used platforms for enzyme immobilization. Silica, organic microparticles, and metal–organic frameworks (MOFs) are an example of these platforms. − MOFs consist of metal cores and organic ligands, and due to their high active surface, adjustable cavities, and resistance to high temperature and chemicals, they are a suitable substrate for enzyme immobilization. , …”

Section: Introductionmentioning

confidence: 99%

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One-Pot Synthesis of 1,3,5-Trisubstitued Pyrazoles via Immobilized Thermomyces lanuginosus Lipase (TLL) on a Metal–Organic Framework

Rangraz,

Amini,

Habibi

2024

ACS Omega

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A regioselective enzyme-catalyzed system is selected for the synthesis of 1,3,5-trisubstituted pyrazole derivatives by adding phenyl hydrazines, nitroolefins, and benzaldehydes. The reaction is performed in a one-pot vessel with a yield ranging from 49 to 90%. TLL@MMI, immobilized Thermomyces lanuginosus lipase (TLL) on a multivariate of MOF-5/IRMOF-3 (MMI), showed good performance for the catalysis of this reaction. The prepared biocatalyst was characterized by FTIR, XRD, SEM, and EDX. The thermal and solvent stability of TLL@MMI was investigated in MeOH and EtOH after 24 h incubation. In the presence of 100% concentrations of EtOH, TLL@MMI has 80% activity.

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Section: Introductionmentioning

confidence: 99%

“…One of these methods is enzyme immobilization. 27 , 28 Porous substrate is one of the most widely used platforms for enzyme immobilization. Silica, organic microparticles, and metal–organic frameworks (MOFs) are an example of these platforms.…”

Section: Introductionmentioning

confidence: 99%