“…Stam (2015Stam ( , 2018, taking hints from the pioneering work of North (1991) and the literature on the topic, provided a rather complete description of the factors that can, together, affect entrepreneurship. He, therefore, made a distinction between framework conditions (formal institutions, informal institutions (e.g., entrepreneurial culture), demands for new goods and physical infrastructure) that are linked to the value creation process within EE, and systemic conditions (networks of entrepreneurs, leadership, finance, talent, knowledge and support services) that are specifically connected to the start-up process (Stam 2015(Stam , 2018Brown and Mawson 2019). Despite the distinctions briefly reported, the factors are intended to interact among themselves (Stam 2018;Singh et al 2019) and create aggregate value through virtuous circles (Faggian et al 2017), as interaction is a key, core element of the entrepreneurial ecosystem model.…”