In order to test the efficiency of colleges and universities to carry out innovation and entrepreneurship education and cultivate the innovative talent system required by economic and social development and change, this paper proposes to combine the fuzzy comprehensive evaluation method based on the analytic hierarchy process. First, gather the students’ ideas, then create a set of measures for each measure, count the weight and significance of each measure, and create a set of criteria for the assessment of the educational process of innovation and entrepreneurship. Census of colleges and universities’ innovation and business measurement model based on student perceptions and determining the weight of each measurement scale will help students understand what is more important in evaluating college and universities’ innovation and business education. Other metrics include innovation and training market, it needs approach, design industry analysis examines business, opportunities for school-to-business engagement, innovation, business education, training, entrepreneurship, and platform information. Therefore, in order to improve the innovation and business education of colleges and universities, it is necessary to carefully establish school management, faculty, classes, activities, innovation, business platform, business education environment, support, advocacy mechanism, and so on. We will improve the teaching of innovation and entrepreneurship and focus on training faculty of innovation and business education and focus on strengthening the innovation and entrepreneurship information platform, innovation, and entrepreneurship incubation base.