Wireless multimedia sensor networks (WMSNs) have been improved with the increase of multimedia data. In WMSNs, a centralization problem can occur because of large-size multimedia data. It is necessary to consider device-to-device (D2D) communication. We focus on D2D WMSN based on cellular networks. Sensors in the D2D WMSN can non-orthogonally use a cellular link, which is a wireless communication channel between a sensor and an aggregator, and a D2D link, which is the channel between sensors. As a result, it has more complex interference environments than an ordinary system. Therefore, it is a key factor to manage the varying inter-cell interference effectively for throughput improvement. We propose an interference mitigation scheme that can be applied to D2D WMSN. In the proposed scheme, a cell is separated into six zones and orthogonal frequency is allocated to each zone for cellular links. The frequencies allocated to cellular links are reused by D2D links of neighboring zones. The simulation results show that the throughput of the proposed scheme increases two times compared to a static frequency allocation scheme.