Environmental allergen reduction in asthma management: an overview

Pham, Duy Le; Le, Kieu-Minh; Truong, Diem D. K.; Le, Huyen T. T.; Trinh, Tu H. K.

doi:10.3389/falgy.2023.1229238

Cited by 4 publications

(2 citation statements)

References 152 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Studies have found the effectiveness of strategies on allergen avoidance including asthma control education, home management, and air filter installation. 9 , 10 For example, interventions involving home visits, pest control, and air circulation management have resulted in statistically significant improvements in asthma control, quality of life, and environmental conditions. 13 Similarly, targeted home environmental programs have reduced the number of asthma triggers.…”

Section: Introductionmentioning

confidence: 99%

“…7 Housing conditions, laden with dust mites, cockroaches, rodents, molds, and pet dander, are significant contributors to asthma morbidity. [8][9][10] More than 92% of the homes contain at least one allergen in dust, emphasizing widespread exposure to indoor allergens. 11 Tenant behavior, including smoking and combustion of nitrogen oxides, further aggravates indoor asthma triggers.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Effectiveness of Asthma Home Management Manual and Low-Cost Air Filter on Quality of Life Among Asthma Adults: A 3-Arm Randomized Controlled Trial

Muanprasong,

Aqilah,

Hermayurisca

et al. 2024

JMDH

View full text Add to dashboard Cite

Background Asthma affects the quality of life (QoL) of millions of people worldwide. Effective control is paramount to a decline in prevalence and severity. To address this, we aimed to investigate the effectiveness of an asthma home management manual and low-cost air filter in improving resource-limited settings. Patients and Methods This randomized controlled trial was conducted between March to July 2022. The participants were 18–55 years old outpatient with asthmatic patients. A total of 114 participants were recruited and randomly assigned to three groups: home management only, home management and air filtering, and control. Validated measurement tools were applied, and the Wilcoxon test was used to evaluate changes in QoL. Results Asthma burden was found in at least one-third of participants in each group. At baseline, there was no difference in mAQLQ scores among participants in all group allocations ( p -value > 0.05), and the air filter group had an increase in the total mAQLQ score ( p -value = 0.044) and post-intervention activity quality of life ( p -value = 0.002). The environmental quality of life increased post-intervention ( p -value = 0.004) and remained higher after four weeks of follow-up compared to baseline ( p -value = 0.041) in the home management group participants. Conclusion The findings indicate that the enforcement of a home management manual and the application of low-cost filters in air circulation systems offer advantages in improving the quality of life of patients with moderate and mild asthma.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Effectiveness of Asthma Home Management Manual and Low-Cost Air Filter on Quality of Life Among Asthma Adults: A 3-Arm Randomized Controlled Trial

Muanprasong,

Aqilah,

Hermayurisca

et al. 2024

JMDH

View full text Add to dashboard Cite

show abstract

The Climate‐Asthma Connection: Examining the Influence of Climate Change Anxiety on Asthma Control and Quality of Life: A Multi‐National Study

Atta,

El‐Sayed,

Taleb

et al. 2024

Journal of Advanced Nursing

View full text Add to dashboard Cite

AimsThis study aims to identify the impact of climate change anxiety and asthma control on asthmatics' quality of life and examine the moderating role of climate change anxiety in this linkage.MethodA multi‐national cross‐sectional study was conducted in four Arabian countries on 1266 asthmatics selected by convenience sampling. Data were collected from November 2023 to February 2024 using a climate anxiety scale, mini‐asthma quality of life questionnaire, and an asthma control questionnaire.ResultsClimate anxiety was higher among middle‐aged participants, as well as those with longer disease durations and previous hospitalisations. Climate anxiety showed strong negative correlations with asthma control (r = −0.704, p ≤ 0.05) and asthma quality of life (r = − 0.638, p ≤ 0.05). Climate anxiety and asthma control are powerful predictors of quality of life among asthmatics. Climate anxiety moderates the relationship between asthma control and quality of life, making it less positive (B = −0.094, p > 0.001). Covariates such as gender, age, comorbidities, employment status, disease duration, and previous hospitalisation showed significant associations with asthma quality of life.Implications for Nursing PracticeAssessment and mitigation of climate anxiety among asthmatics is a key strategy for controlling asthma and improving the quality of life. So, nurses must incorporate climate anxiety assessment into the care plan for asthmatics.ImpactClimate change is a global concern, and insights into how climate‐related psychological stressors exacerbate asthma symptoms and overall health outcomes are necessary. The findings provide actionable data for healthcare professionals to underscore the need for integrated healthcare approaches considering environmental and psychological factors.Reporting MethodThis study adheres to strengthening the reporting of observational studies in epidemiology (STROBE) statement.Patient or Public ContributionClients with asthma across multiple nationalities actively contributed to our paper.

show abstract

Effect of PM 2.5 exposure on susceptibility to allergic asthma in elderly rats treated with allergens

Zhao,

Zhou,

Ding

et al. 2024

Preprint

View full text Add to dashboard Cite

Fine particulate matter 2.5 (PM2.5) is an environmental pollutant in the atmosphere that is closely associated with asthma. Elderly patients have a high incidence of asthma with a long course of illness. Our previous studies revealed that exposure to PM2.5 reduces lung function and exacerbates lung damage in elderly rats. In the present study, we investigated whether PM2.5 exposure influences susceptibility to allergic asthma in elderly rats. Brown-Norway elderly rats were treated with ovalbumin (OVA) for different durations before and after PM2.5 exposure. The results from pulmonary function tests and histopathology revealed that early exposure to allergens prior to PM2.5 exposure increased susceptibility to airway hyperresponsiveness and led to severe lung injury in elderly asthmatic rats. Cytokine microarray analysis revealed that most cytokines and chemokines were upregulated in OVA-treated rats before and after PM2.5 exposure. Cytological analysis revealed that the number of EOS did not change, whereas the amounts of NEU, WBC, LYM, and MON in the lung lavage fluid of OVA-treated rats were significantly greater than those in the lung lavage fluid of control rats before and after PM2.5 exposure, suggesting that PM2.5 affects noneosinophilic asthma in elderly rats. ELISA results from the plasma and lung lavage fluid revealed that the levels of IgG1, IgE, IgG2a and IgG2b were significantly elevated in OVA-treated rats before and after PM2.5 exposure, whereas the level of IgG2b in the lung lavage fluid was significantly lower in those treated with OVA before PM2.5 exposure than in those after PM2.5 exposure. We performed a non-targeted metabolomic analysis of plasma and identified 202 metabolites. A total of 31 differentially abundant metabolites were screened, and 10 metabolites and 11 metabolic pathways were detected in only OVA-treated rats before PM2.5 exposure. Specifically, there were positive or negative correlations between the levels of Th2-associated cytokines (IL-4, IL-5, and IL-13) and the levels of 6 metabolites in the OVA-treated group before PM2.5 exposure, whereas the levels of IL-4 and IL-5 were negatively correlated with the levels of 5 metabolites in the OVA-treated group after PM2.5 exposure. Our findings suggest that PM2.5 exposure could influence the susceptibility of allergic asthma in response to allergens in elderly rats, possibly through changes in plasma metabolites.

show abstract

Environmental allergen reduction in asthma management: an overview

Cited by 4 publications

References 152 publications

Effectiveness of Asthma Home Management Manual and Low-Cost Air Filter on Quality of Life Among Asthma Adults: A 3-Arm Randomized Controlled Trial

Effectiveness of Asthma Home Management Manual and Low-Cost Air Filter on Quality of Life Among Asthma Adults: A 3-Arm Randomized Controlled Trial

The Climate‐Asthma Connection: Examining the Influence of Climate Change Anxiety on Asthma Control and Quality of Life: A Multi‐National Study

Effect of PM 2.5 exposure on susceptibility to allergic asthma in elderly rats treated with allergens

Contact Info

Product

Resources

About