Environmental and Physiological Factors Affecting Lead and Cadmium Levels in Deciduous Teeth

Bayo, Javier; Moreno‐Grau, Stella; Martı́nez, Marı́a José; Angosto, José M.; Pérez, José Jesús Guillén; García‐Marcos, Luis; Moreno-Clavel, J.

doi:10.1007/s002440010245

Cited by 21 publications

(2 citation statements)

References 36 publications

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“…Similar observations were made by authors from Spain [ 33 ] evaluating the relationship between place of residence and cadmium content in hard tissue of deciduous teeth, who confirmed the existence of a positive correlation between high environmental contamination and a higher concentration of a pathogenic element in enamel and dentin.…”

Section: Discussionsupporting

confidence: 87%

Evaluation of Metal Ion Concentration in Hard Tissues of Teeth in Residents of Central Poland

Wychowański

Małkiewicz

2017

BioMed Research International

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Objectives. The aim of the study was an assessment of the content of trace elements in enamel and dentin of teeth extracted in patients residing in urban and agricultural areas of Poland. Methods. The study included 30 generally healthy patients with retained third molars. 65 samples of enamel and dentin from individuals living in urban areas and 85 samples of enamel and dentin from individuals living in agricultural areas were prepared. The content of manganese, lead, cadmium, and chromium in the studied enamel and dentin samples from retained teeth was determined by Graphite Furnace Atomic Absorption Spectrometry. In the process of statistical hypothesis testing, the level of significance was assumed at α = 0.05. Results. A comparative analysis of the data showed that enamel and dentin of inhabitants of industrialized areas contain significantly higher amounts of lead and cadmium than hard tissues of teeth in residents of agricultural areas and comparable amounts of manganese and chromium. Significance. It appears that hard tissues of retained teeth may constitute valuable material for assessment of long-term environmental exposure to metal ions. The study confirms that the risk of exposure to heavy metals depends on the place of residence and environmental pollution.

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Section: Discussionsupporting

confidence: 87%

Evaluation of Metal Ion Concentration in Hard Tissues of Teeth in Residents of Central Poland

Wychowański

Małkiewicz

2017

BioMed Research International

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“…Environmental point sources of exposure have been shown to be related to tooth concentrations as a function of age and proximity to the source [ 14 – 16 ]. Further, physiological factors (i.e., gender, tooth type, and weight) as well as behavioral factors (i.e., socioeconomic status, home antiquity, and nail biting habits) have been shown to also explain levels of lead and cadmium in teeth [ 17 , 18 ].…”

Section: Introductionmentioning

confidence: 99%

Organic Compounds Detected in Deciduous Teeth: A Replication Study from Children with Autism in Two Samples

Palmer¹,

Heilbrun²,

Camann

et al. 2015

Journal of Environmental and Public Health

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Biological samples are an important part of investigating toxic exposures and disease outcomes. However, blood, urine, saliva, or hair can only reflect relatively recent exposures. Alternatively, deciduous teeth have served as a biomarker of early developmental exposure to heavy metals, but little has been done to assess organic toxic exposures such as pesticides, plastics, or medications. The purpose of our study was to determine if organic chemicals previously detected in a sample of typically developing children could be detected in teeth from a sample of children with autism. Eighty-three deciduous teeth from children with autism spectrum disorders (ASD) were chosen from our tooth repository. Organic compounds were assessed using liquid chromatography tandem mass spectrometry and gas chromatography methods. Consistent with a prior report from Camann et al., (2013), we have demonstrated that specific semivolatile organic chemicals relevant to autism etiology can be detected in deciduous teeth. This report provides evidence that teeth can be useful biomarkers of early life exposure for use in epidemiologic case-control studies seeking to identify differential unbiased exposures during development between those with and without specific disorders such as autism.

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Metal Contamination and the Epidemic of Congenital Birth Defects in Iraqi Cities

Al-Sabbak

Ali

Savabi

et al. 2012

Bull Environ Contam Toxicol

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Between October 1994 and October 1995, the number of birth defects per 1,000 live births in Al Basrah Maternity Hospital was 1.37. In 2003, the number of birth defects in Al Basrah Maternity Hospital was 23 per 1,000 live births. Within less than a decade, the occurrence of congenital birth defects increased by an astonishing 17-fold in the same hospital. A yearly account of the occurrence and types of birth defects, between 2003 and 2011, in Al Basrah Maternity Hospital, was reported. Metal levels in hair, toenail, and tooth samples of residents of Al Basrah were also provided. The enamel portion of the deciduous tooth from a child with birth defects from Al Basrah (4.19 μg/g) had nearly three times higher lead than the whole teeth of children living in unimpacted areas. Lead was 1.4 times higher in the tooth enamel of parents of children with birth defects (2,497 ± 1,400 μg/g, mean ± SD) compared to parents of normal children (1,826 ± 1,819 μg/g). Our data suggested that birth defects in the Iraqi cities of Al Basrah (in the south of Iraq) and Fallujah (in central Iraq) are mainly folate-dependent. This knowledge offers possible treatment options and remediation plans for at-risk Iraqi populations.

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Environmental and Physiological Factors Affecting Lead and Cadmium Levels in Deciduous Teeth

Cited by 21 publications

References 36 publications

Evaluation of Metal Ion Concentration in Hard Tissues of Teeth in Residents of Central Poland

Evaluation of Metal Ion Concentration in Hard Tissues of Teeth in Residents of Central Poland

Organic Compounds Detected in Deciduous Teeth: A Replication Study from Children with Autism in Two Samples

Metal Contamination and the Epidemic of Congenital Birth Defects in Iraqi Cities

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