Environmental applications of luminescent metal nanoclusters

Pebdeni, Azam Bagheri; Kudahi, Saeed Nazari; Hosseini, Morteza

doi:10.1016/b978-0-323-88657-4.00011-9

Cited by 2 publications

(1 citation statement)

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“…The sensing principle of this method is based on the peroxidase catalytic reaction of hydrogen peroxide (H 2 O 2 )-mediated oxidation of colorimetric substrates such as 3,3 0 ,5,5 0 tetramethylbenzidine and azinobis (3-ethylbenzothiazoline)-6-sulfonic acid (ABTS), generating distinguish color products. [124][125][126] An enzyme-linked probe is used. When the target DNA binds to the probe, it brings the enzyme into proximity, initiating an enzymatic reaction that generates a colored product.…”

Section: Colorimetric Detectionmentioning

confidence: 99%

Point‐of‐Care Testing (POCT) Devices for DNA Detection: A Comprehensive Review

Mahardika,

Naorungroj,

Khamcharoen

et al. 2023

Advanced NanoBiomed Research

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DNA chips play a crucial role in point‐of‐care diagnostics by enabling rapid and accurate detection of genetic information. These chips offer high sensitivity and selectivity, allowing for the identification of specific DNA sequences associated with diseases and pathogens. Integration into lab‐on‐chip platforms streamlines and miniaturizes diagnostic workflows, paving the way for cost‐effective, portable, and user‐friendly testing devices that can revolutionize healthcare delivery. In this review, a comprehensive description of the platforms utilized in DNA analysis, including microfluidic devices and integrated DNA chips, is provided. It explores the selection and immobilization of DNA probes for improved selectivity. Additionally, it covers diverse detection techniques such as optical detection (colorimetry and fluorescence) and electrochemical techniques. In these discussions, it is aimed to provide a thorough understanding of the current state of the art in DNA biosensor‐integrated lab‐on‐chip technology for point‐of‐care testing. The continued advancements in DNA chip technology hold immense promise for the development of next‐generation point‐of‐care diagnostics, where integrated sample preparation and rapid results generation can further enhance patient outcomes and contribute to the effective management of diseases.

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Section: Colorimetric Detectionmentioning

confidence: 99%