Environmental Aspects of Radiopharmaceuticals Extraction and Translocation of Ra 223 in Plants

Kozempel, Ján; Vlk, Martin; Nykl, Pavel; Psondrova, Sarka; Smrček, Stanislav; Krmelová, Tereza

doi:10.15224/978-1-63248-114-6-27

Cited by 2 publications

(2 citation statements)

References 9 publications

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“…Table 1 Factor loadings (the highest loadings are marked by bold) mind that BIOWIN 1 and BIOWIN 2 describe biodegradation under aerobic conditions it is very logical to expect that compounds with low accumulation ability will stay principally into water phase where aerobic biodegradation is the most probable. This is the probable reason in PCA BIOWIN 1 and BIOWIN 2 to form separate group PC2 which describe very well molecules in C1 (see Table A1 in supplementary 1, 2,4,5,17,22,19,18,20,16,21) object cluster (Fig. 2).…”

Section: Factor Analysismentioning

confidence: 85%

“…The majority of currently available RP are composed of three main components: a targeting biomolecule (bio-vector), the bifunctional agent (conjugation, pharmacokinetic), and the radioisotope (therapy or diagnostic) [15,16]. Carrying out environmental impact studies using existing models [17,18] will provide reliable data about environmental behaviour of the radionuclides without information for the effect of their non-radioactive part. This organic part of RP can be accepted as radiopharmaceutical residuals (RPR) which will cause for longer time effect on nature [19,20] than conjugated radioisotopes (short half-lives from minutes to days).…”

Section: Introductionmentioning

confidence: 99%

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Environmental Effect of Potential Radiopharmaceuticals Residuals

Todorov

Nedyalkova

Simeonov

2020

Ecological Chemistry and Engineering S

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Driven by the current development of quantitative structure-properties relationship (QSPR) methods in the environmental science, we proposed an approach based on chemometric tools for selection of appropriate physicochemical parameters of radiopharmaceuticals residuals for predicting of partitioning, hazards and biodegradation of such compounds into the environment or into wastewater treatment plant. The present scheme was successfully applied for prediction of missing values for 24 different physicochemical and assessment response of the environmental fate descriptors for 11 tetrazine derivatives and 12 cyclooctene derivatives. The multivariate statistics was also proved to be useful in the evaluation of the obtained modelling results for identification of the ecological effect of radiopharmaceuticals residuals. The presented approach can be one of the first steps and support tools in the assessment of chemicals in terms of their environmental impact. The problem studies are significant since it allows a special point of view to the underestimated radiopharmaceutical pollutants.

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Section: Factor Analysismentioning

confidence: 85%

Section: Introductionmentioning

confidence: 99%

Environmental Effect of Potential Radiopharmaceuticals Residuals

Todorov

Nedyalkova

Simeonov

2020

Ecological Chemistry and Engineering S

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Approaches to Nanoparticle Labeling: A Review of Fluorescent, Radiological, and Metallic Techniques

Chen

et al. 2023

Environ. Health

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Nanomaterials are widely used in commercial products, resulting in the release of nanoscale particles into the environment. This raises concerns about their potential exposure risks in complex biological matrices. Most attempts use engineered nanomaterials (ENMs) to mimic the biological behavior of nanoparticles in the environment, and labeling of ENMs by sensors is a commonly used approach for sensitive detection and tracking of ENMs in organisms. However, due to the distinct physicochemical properties of nanoparticles, different labeling approaches have been developed, each with varying applicability. In this Review, we summarize the three main types of labeling methods used for nanoparticles: fluorescent, radiological, and metallic labeling. We discuss their labeling mechanisms, efficiency, stability, target nanoparticles, and applicability in different organism models. Finally, we propose a labeling scheme for specific nanoparticles. Overall, this Review provides a comprehensive overview of the advances in nanoparticle labeling techniques and their potential applications in environmental and health studies.

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Environmental Aspects of Radiopharmaceuticals Extraction and Translocation of Ra 223 in Plants

Cited by 2 publications

References 9 publications

Environmental Effect of Potential Radiopharmaceuticals Residuals

Environmental Effect of Potential Radiopharmaceuticals Residuals

Approaches to Nanoparticle Labeling: A Review of Fluorescent, Radiological, and Metallic Techniques

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