Mapping the susceptibility of earthquake-induced soil liquefaction at the continental scale is a challenge. Susceptibility of soils to liquefaction is the tendency of certain geomaterials to undergo a severe stiffness degradation and loss of shear strength. The latter could be induced by cyclic loading induced by seismic events. The liquefaction surface evidence is a local phenomenon, and detailed geotechnical field investigations are not available for regional studies, not to mention at continental scales. The literature review shows earthquake-induced soil liquefaction evidence in several European countries, yet, a comprehensive picture of the susceptibility at the European scale is not available. This work aims to develop a methodology to assess the earthquake-induced soil liquefaction susceptibility in Europe using geospatial parameters weighted via the Analytic Hierarchy Process (AHP). The major outcome of the study is a novel Liquefaction Susceptibility map of Europe (LSE), based on the building of ten different European macro-units for earthquake-induced soil liquefaction. These European macro-units have been delineated in this work in order to be homogenous areas from the geological, physiographical, and geomorphological points of view. The adopted input parameters are the depositional environment of the sediments, the distance from water bodies (coast and rivers), and the compound topographic index (as a proxy of the soil saturation). The resolution of the LSE map is 900 × 900 m. The results have been cross-compared with soil liquefaction susceptibility maps available for a region of Greece (i.e. Thrace), Portugal, Bulgaria, and sites where liquefaction manifestations occurred across Europe. The LSE can be adopted to identify at large scale the areas susceptible to liquefaction including also the territories across Europe characterized by low seismicity and potentially affected by anthropogenic seismicity.