IntroductionFever is one of the most frequent reasons for paediatric consultations in Burkina Faso, but health care-seeking behaviours and the factors associated with health care-seeking in the event of childhood fever are poorly documented. This study aims to help fill this gap.MethodsThis study used the data from the baseline and endline surveys conducted to evaluate the impact of the Performance-Based Financing (PBF) program in Burkina Faso. Univariate and multivariate binary logistic regression analyses were used to identify the factors associated with appropriate healthcare-seeking for childhood fever. Odds ratios (ORs) were estimated to assess the strength of associations and used 95% confidence intervals for significance tests. Data were cleaned, coded and analysed using Stata software version 16.1.ResultsAmong the children under five who had a fever, 75.19% and 79.76 sought appropriate health care in 2013 and 2017, respectively. Being 24–59 months old (AOR: 0.344, 95% CI: 0.182–0.649 in 2013) and 79,2% (AOR: 0. 208, 95% CI: 0.115–0.376 in 2017), living in a very wealthy household households (AOR: 2.014, 95% CI: 1.149–3.531 in 2013 and AOR: 2.165, 95% CI: 1.223–3.834 in 2017), having a mother with a secondary or higher level of education or having made at least four antenatal care visits were significantly associated with seeking appropriate health care for childhood fever. Living in an area where the health facility is safe was also significantly associated with seeking appropriate care for childhood fevers.ConclusionThe findings underscore the need for interventions that would improve appropriate health care-seeking among mothers for their children. These interventions could include mothers’ sensitization to the benefits of modern health care use, increasing women’s education, improving household wealth status, improving the level of prenatal and postnatal care use and improving health care quality and safety in health facilities.