Environmental factors and risk of developing paediatric inflammatory bowel disease — A population based study 2007–2009

Jakobsen, Christian; Pærregaard, Anders; Munkholm, Pia; Wewer, Vibeke

doi:10.1016/j.crohns.2012.05.024

Cited by 97 publications

(88 citation statements)

References 50 publications

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“…Both factors indicate that hormonal influences also may play a role at least for the risk of disease flares. • For breastfeeding, conflicting results have been reported [20,[67][68][69][70][71] . A meta-analysis could not conclusively decide whether there is a protective or even diseaseaggravating effect [72] .…”

Section: Environmental Factors Known To Play a Role For Disease Flaresmentioning

confidence: 83%

The Search for Causative Environmental Factors in Inflammatory Bowel Disease

Rogler

Zeitz

Biedermann

2016

Dig Dis

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Section: Environmental Factors Known To Play a Role For Disease Flaresmentioning

confidence: 83%

The Search for Causative Environmental Factors in Inflammatory Bowel Disease

Rogler

Zeitz

Biedermann

2016

Dig Dis

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“…Moreover, some studies have demonstrated an inverse correlation between consumption of citrus fruits, fruit and vegetable juices vs. incidence of CD and UC [7,8]. According to the study carried out in Denmark in 118 patients with IBD and in several-hundred controls, high sugar intake significantly increased the risk of IBDs while consumption of large amounts of vegetables had protective effects [9]. To maintain the integrity of the intestinal mucosa, hence the intestinal barrier, it is essential to consume the products rich in fibre.…”

Section: Effects Of Diet On the Ibd Incidence And Coursementioning

confidence: 99%

Advances in Nutrition of Patients with Inflammatory Bowel Diseases

Dworzański¹,

Celiński²,

Dworzanska³

et al. 2016

J Nutr Food Sci

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Inflammatory bowel diseases (IBDs) are multifactorial disorders whose aetiology and pathogenesis have not been fully elucidated. Their occurrence is affected by genetic and environmental factors. Amongst the environmental factors, proper diet seems to be crucial, both in the healthy population and in patients during disease exacerbations and remissions. Depending on their severity, duration and extent of inflammatory lesions, IBD exacerbations result in some dietary deficits. Appropriate supplementation can effectively correct the deficits; in some cases, mainly in CD, nutritional therapy can be equally effective for inducing remissions as pharmacotherapy. Enteral feeding is recommended in each case without important contraindications for its use. Counteracting the caloric, protein and microelement deficiencies is pivotal for inhibition of disease pathogenesis and for enhancement of the antiinflammatory response of the organism. The present paper is to present simply review and analyse of recent reports regarding nutrition in patients with CD and UC as well as to discuss recommended nutritional management in certain IBD course-associated conditions. Nutritional therapy is a key element of management of IBD patients.

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“…Although the precise aetiology of CD, as well as the forces behind the changing epidemiology, remain unknown, most hypotheses propose that environmental factors are the predominant contributing force in the rise of CD rates and earlier disease onset [19,49,50] . The changing diet habits of Asian populations is one factor that may be responsible for the rising incidence [34,51] .…”

Section: Role Of Environmental Factors In CD Pathogenesis and Changinmentioning

confidence: 99%

Changing Patterns in the Epidemiology of Crohn Disease

Alhagamhmad

Leach

Lemberg

et al. 2015

Journal of Gastroenterology and Hepatology Research

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Crohn disease is a chronic inflammatory disorder that primarily affects the alimentary tract. It is an increasingly global health concern, with recent data indicating rising rates across many countries in the world, along with a growing prevalence in childhood. Numerous reports indicate that Crohn disease is no longer confined to Western countries, with many reports of diagnosis in other regions including less developed nations. Changes in dietary patterns, along with other environmental factors, appear to account for these recent changes in the patterns of Crohn disease epidemiology. The objective of this work was to review current available literature concerning the epidemiology of Crohn disease and to consider the possible roles of environmental factors that may be implicated in these changing patterns. Widespread data indicates increasing incidence of Crohn disease in many countries across the world. The reasons for these rapid changes in the epidemiology of Crohn disease are not clearly understood. However, environmental changes appear to the most important factors for these recent changes.

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Environmental factors and risk of developing paediatric inflammatory bowel disease — A population based study 2007–2009

Abstract: We identified several risk and protective factors for developing IBD. Studies on the influence of environmental factors are important in our understanding of aetiology and phenotypes of paediatric IBD.

Cited by 97 publications

References 50 publications

The Search for Causative Environmental Factors in Inflammatory Bowel Disease

The Search for Causative Environmental Factors in Inflammatory Bowel Disease

Advances in Nutrition of Patients with Inflammatory Bowel Diseases

Changing Patterns in the Epidemiology of Crohn Disease

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