Environmental health hazard of arsenic on epididymis and ductus deferens in male Black Bengal Goats

Wares,; Awal,; Nasrin, Morsheda; Siddiqi, Manhal

doi:10.3329/jbau.v11i1.18220

Cited by 3 publications

(2 citation statements)

References 13 publications

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“…The mass of testes is an important index of reproductive toxicants (Aman, ), and reduction in mass of testes may be due to elimination of germ cells (Chapin & Lamb, ). However, no significant difference was reported in the mean values of weight, length, width and breadth of both testes as well the epididymis and ductus deferens in naturally arsenic‐affected goats (Wares, Awal, Nasrin, & Siddiqi, ; Wares et al., ). This difference might be due to relatively low doses of arsenic during natural exposure.…”

Section: Discussionmentioning

confidence: 99%

Protective effects of vitamin E on sodium arsenite-induced toxicity, testicular measurements and histopathological studies of testes in Teddy goat bucks

et al. 2016

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The objective of this study was to investigate the toxic effects of arsenic on testicular measurements and histology of adult Teddy goats bucks and to examine whether these toxic effects are scavenged by vitamin E. Twelve adult Teddy goat bucks were divided randomly into three groups, A, B and C. Group A was kept as control, the B was given sodium arsenite 5 mg/kg BW per day, and group C was fed with vitamin E 200 mg/kg BW per day + arsenic 5 mg/kg BW per day. This treatment was continued for 84 days. Analysis of data revealed that the testicular measurements (scrotal circumference, width, length and weight) were significantly reduced in arsenic-treated animals, whereas there were ameliorating effects of vitamin E on these parameters. The major histopathological changes were present in the form of loss of germinal epithelium, atrophy of Leydig cells and vacuolations. Vitamin E in combination with sodium arsenite increased the active spermatogenesis as well as restoration of germinal epithelium. It can be concluded from the present findings that sodium arsenite causes toxicity in the male reproductive system of Teddy goat bucks with major changes in parenchyma of testes. Supplementation of vitamin E has protective effects on the toxicity of sodium arsenite on the reproductive system of male Teddy goat bucks.

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Section: Discussionmentioning

confidence: 99%

Protective effects of vitamin E on sodium arsenite-induced toxicity, testicular measurements and histopathological studies of testes in Teddy goat bucks

et al. 2016

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“…In goats, it has been found that consuming water contaminated with arsenic can cause damage to the body and the physiological condition [ 12 ], because exposure to arsenic results in its deposition in different body tissues such as the heart, muscles, kidneys and liver of animals, which produces different toxic effects in these tissues [ 13 ]. On the other hand, there are reports that arsenic also causes damage at the reproductive level; in fact, damage has been found in the epididymis and vas deferens [ 14 ], as well as in sperm quality [ 11 , 15 , 16 ]. These alterations caused by the high levels of arsenic in the animal’s organism can be attributed to the oxidative stress it exerts, as it can damage DNA, leading to a cascade of events, some of which can be adverse.…”

Section: Introductionmentioning

confidence: 99%

Counteracting the Toxic Hidroarsenicism Effects upon Reproductive-Physiological Outcomes in Male Goats: The Selenium and Vitamin-E Mitigation Approach

Ortega-Morales,

Cueto-Wong,

Velez-Monroy

et al. 2023

Animals

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This study was to evaluate whether selenium and vitamin-E counteract the toxic effects of arsenic on reproductive aspects and physiological conditions of male goats. Male goats [Criollo, n = 20, 4–5 yr-old, 72 kg live weight (LW)] were distributed in homogeneous groups (n = 5), and received during 12 weeks: (1) Sodium arsenite 2 mg/kg of LW/day (AG, LW = 69 kg); (2) Sodium selenite 6 mg + vitamin-E 420 I.U. every 14 days during the 12 weeks (SG, LW = 68 kg); (3) Both AG and SG treatments (ASG, LW = 77 kg); and (4) 1 mL of physiological solution every 14 days during the 12 weeks (CG, LW = 72 kg). The animals had access to water from a well with a concentration of 35 μg/L of arsenic. The SG had the highest percentage of sperm viability (80.6%) followed by the CG, ASG (74.7; p > 0.05), and AG (64.3; p ≤ 0.05). The ASG and SG had a lower heart rate as compared to the CG and AG (58.8, 58 vs. 65.4, 63.5; respectively, p ≤ 0.05). The CG and SG showed a lower respiratory rate than the AG and ASG (19.2, 18.7 vs. 22.1, 21.0, respectively; p ≤ 0.05). Selenium and vitamin-E were efficient in reducing the damage caused by sodium arsenite in sperm quality and maintaining heart and respiratory rates and increases in odor in male goats.

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A systematic review of pre-clinical and clinical research reports on small ruminants published during the last six decades in the then East Pakistan and in Bangladesh

Samad¹

2019

JVMOHR

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Background: A dozen of veterinary academic institutions offer degree courses with pre-clinical and clinical studies and conduct research works but their activities are not coordinated and unified in Bangladesh. An attempt has been made to review the pre-clinical and clinical research reports in small ruminants which would help the concerned academicians, research scientists and research funded organizations to update their knowledge of specialization and use this reference as a starting point for formulation of the future academic and research guidelines. Objectives: The main objectives are to provide an integrated, systematic overview of all the available published research reports on the pre-clinical and clinical aspects of small ruminants to update knowledge and to identify research insights, existing gaps and future research directions. Materials and Methods: The available research reports on pre-clinical and clinical aspects of small ruminants published mainly in journals during the last six decades in Bangladesh from 1966 to 2019 were reviewed. Data obtained were analyzed statistically based on pre-clinical and clinical subjects, host species, age, breeds, clinical prevalence and decade-wise to assess the rate of publication. Results: Of the 665 selected articles, 621 research papers published on small ruminants during the last six decades from Bangladesh were systematically reviewed, of which 340 (54.75%) articles reported as pre-clinical and 281 (45.25%) on clinical aspects with significantly higher rates in goats (n = 486; 78.26%) than sheep (n = 135; 21.74%). Out of 126 recorded clinical diseases and disorders in small ruminants, 125 (99.21%) reported in goats and 44 (34.92%) in sheep, with 43 (34.13%) common in both goats and sheep but only pregnancy toxaemia (0.79%) reported in sheep. The influence of age and breeds on the prevalence of clinical diseases and disorders associated with their morbidity and mortality are described and discussed. Conclusions: This unified review article would serve as a guide for the veterinary medical academicians, research scientists and organizations for future studies and research directions. The disease profiles and their morbidity and mortality status in small ruminants might help the practicing veterinarians, government, human health care providers and neighboring countries who may need to take action.

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Environmental health hazard of arsenic on epididymis and ductus deferens in male Black Bengal Goats

Cited by 3 publications

References 13 publications

Protective effects of vitamin E on sodium arsenite-induced toxicity, testicular measurements and histopathological studies of testes in Teddy goat bucks

Protective effects of vitamin E on sodium arsenite-induced toxicity, testicular measurements and histopathological studies of testes in Teddy goat bucks

Counteracting the Toxic Hidroarsenicism Effects upon Reproductive-Physiological Outcomes in Male Goats: The Selenium and Vitamin-E Mitigation Approach

A systematic review of pre-clinical and clinical research reports on small ruminants published during the last six decades in the then East Pakistan and in Bangladesh

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