Environmental impacts of conventional and additive manufacturing for the production of Ti-6Al-4V knee implant: a life cycle approach

Lyons, R.; Newell, Anthony; Ghadimi, Pezhman; Papakostas, Nikolaos

doi:10.1007/s00170-020-06367-7

Cited by 41 publications

(23 citation statements)

References 55 publications

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“…2012 ), and anesthetic equipment at two hospitals ( McGain et al. 2017 ); c ) items specific to particular procedures or specialties, such as titanium alloy knee implants ( Lyons et al. 2021 ), custom packs used to deliver newborns ( Campion et al.…”

Section: Resultsmentioning

confidence: 99%

“…Other functional units employed included: per item (disposable custom packs, Campion et al. 2015 ; knee implants, Lyons et al. 2021 ), per kilogram (medical gloves, Weisz et al.…”

Section: Resultsmentioning

confidence: 99%

“…Twenty-eight studies assessed environmental impact contributions from equipment used in surgical settings, including a) general surgical items, such as gowns (Carre 2008;Van den Berghe and Zimmer 2011;, drapes (Vozzola et al 2018), scrubs (Mikusinska 2012), scissors (Ibbotson et al 2013), suction receptacles (Ison and Miller 2000), deep vein thrombosis (DVT) compression sleeves, pulse oximeters, LigaSure devices, harmonic scalpels, endoscopic trocars, arthroscopic shavers, scissor tips (Unger and Landis 2016); b) anesthetic equipment, such as anesthetic drug trays (McGain et al 2010), laryngeal mask airways (LMA; Eckelman et al 2012;Liang 2019), laryngoscope blades and handles (Sherman et al 2018), central venous catheter insertion kits (McGain et al 2012), and anesthetic equipment at two hospitals (McGain et al 2017); c) items specific to particular procedures or specialties, such as titanium alloy knee implants (Lyons et al 2021), custom packs used to deliver newborns (Campion et al 2015), ureteroscopes (Davis et al 2018), spinal fusion instrument sets (Leiden et al 2020), and single-use medical devices and products used during hysterectomy (Unger et al 2017); and d) items used in, but not specific to, surgery, such as personal protective equipment (masks, gloves, aprons, gowns, and face shields; Rizan et al 2021), surgical face masks (Allison et al 2020;Lee et al 2021;Schmutz et al 2020), medical gloves (Weisz et al 2020), urinary catheters (Stripple et al 2008), sharps containers (Grimmond and Reiner 2012;McPherson et al 2019), and vaginal specula (Donahue et al 2020).…”

Section: Equipment and Materialsmentioning

confidence: 99%

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Operating in a Climate Crisis: A State-of-the-Science Review of Life Cycle Assessment within Surgical and Anesthetic Care

Drew

Christie

Tyedmers

et al. 2021

Environ Health Perspect

103

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BACKGROUND: Both human health and the health systems we depend on are increasingly threatened by a range of environmental crises, including climate change. Paradoxically, health care provision is a significant driver of environmental pollution, with surgical and anesthetic services among the most resource-intensive components of the health system. OBJECTIVES: This analysis aimed to summarize the state of life cycle assessment (LCA) practice as applied to surgical and anesthetic care via review of extant literature assessing environmental impacts of related services, procedures, equipment, and pharmaceuticals. METHODS: A state-of-the-science review was undertaken following a registered protocol and a standardized, LCA-specific reporting framework. Three bibliographic databases (Scopus ® , PubMed, and Embase ® ) and the gray literature were searched. Inclusion criteria were applied, eligible entries critically appraised, and key methodological data and results extracted. RESULTS: From 1,316 identified records, 44 studies were eligible for inclusion. The annual climate impact of operating surgical suites ranged between 3,200,000 and 5,200,000 kg CO 2 e. The climate impact of individual surgical procedures varied considerably, with estimates ranging from 6 to 1,007 kg CO 2 e. Anesthetic gases; single-use equipment; and heating, ventilation, and air conditioning system operation were the main emissions hot spots identified among operating room-and procedure-specific analyses. Single-use equipment used in surgical settings was generally more harmful than equivalent reusable items across a range of environmental parameters. Life cycle inventories have been assembled and associated climate impacts calculated for three anesthetic gases (2-85 kg CO 2 e=MAC-h) and 20 injectable anesthetic drugs (0:01-3:0 kg CO 2 e=gAPI). DISCUSSION: Despite the recent proliferation of surgical and anesthesiology-related LCAs, extant studies address a miniscule fraction of the numerous services, procedures, and products available today. Methodological heterogeneity, external validity, and a lack of background life cycle inventory data related to many essential surgical and anesthetic inputs are key limitations of the current evidence base. This review provides an indication of the spectrum of environmental impacts associated with surgical and anesthetic care at various scales.

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Section: Resultsmentioning

confidence: 99%

“…Other functional units employed included: per item (disposable custom packs, Campion et al. 2015 ; knee implants, Lyons et al. 2021 ), per kilogram (medical gloves, Weisz et al.…”

Section: Resultsmentioning

confidence: 99%

Section: Equipment and Materialsmentioning

confidence: 99%

See 1 more Smart Citation

Operating in a Climate Crisis: A State-of-the-Science Review of Life Cycle Assessment within Surgical and Anesthetic Care

Drew

Christie

Tyedmers

et al. 2021

Environ Health Perspect

103

View full text Add to dashboard Cite

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“…The work does not only focus on electricity consumption but also on the consumption of fluids and materials. In [20] an environmental study to compare electron beam melting (EBM) and rotation of Ti-6Al-4V pieces was elaborated. [25] performed an LCA of Ti-6Al-4V parts to compare direct additive laser manufacturing (CLAD) and machining.…”

Section: State Of the Artmentioning

confidence: 99%

Integration of Environmental Assessment in Process Engineering of Metal Additive Manufacturing Technology

Mrabet

Gaha

Marteau

et al. 2022

Advances in Transdisciplinary Engineering

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Lately researchers have been paying more attention to the environmental aspect, especially since our planet is nowadays threatened by multiple phenomena. In this context as a manufacturing process, the additive manufacturing appeared as a trend in its domain because it’s economic, eliminates raw material waste and allows to make complex shapes, which may not be obtained by conventional manufacturing processes. There are many additive manufacturing processes, this research will focus only on Wire Arc Additive Manufacturing which has an impact on the environment, by consuming energy (for welding, for cooling, moving the nozzle) and gases. In this paper will provide an overview to the different studies related to the environmental aspect of this process, where some have concentrated on the parameters that surround the product, other studies focused on the parameters related to the process. We will group all the ideas to find an application of the process in the context of sustainable development.

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“…This can be carried out using software like OpenLCA, GaBi, SimaPro. A few research works have been reported using this tool for analyzing the environmental impact of 3D printed parts in the field of polymer filaments, automobile and health sector (DeBoer et al , 2021; Lyons et al , 2021; Ma et al , 2021). But, there were no LCA studies found for 3D printed drug delivery systems.…”

Section: Introductionmentioning

confidence: 99%

Investigations of personalized and sustainable approach of oral drug delivery systems through additive manufacturing

Reddy

Elgazzar²,

Sharma

2021

RPJ

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Purpose The purpose of this paper is to print a thermolabile drug-containing tablet using the fused deposition modeling (FDM) technique and analyze its mechanical, pharmaceutical and environmental feasibility using a variety of tests. Design/methodology/approach Ascorbic acid (Vitamin C) is the thermally-sensitive drug impregnated into polyvinyl alcohol excipient using ethanol-water mixture and printed by an FDM printer by varying three parameters without using any external stabilizing agent. Afterward, Taguchi analysis has been performed on these parameters to recognize the significant factors and interactions. Besides this, a regression model has been obtained based on the dissolution data. Various thermo-mechanical and pharmaceutical tests have been carried out to confirm the feasibility. Finally, a life cycle assessment (LCA) analysis has been carried out to compare it with the existing tableting method by considering the environmental impacts. Findings The dissolution profile was found to follow the Korsmeyer-Peppas model, where the drug release occurred both by dissolution and erosion. Further, the infill percent has been found as the most significant parameter. The characterization tests and imaging outputs proved the fidelity of this attempt. Finally, the three-dimensional printed method was found to be more environmentally sustainable than the existing conventional tableting process. Originality/value LCA on a printed tablet is a one-of-a-kind attempt. Thus, this research attempt delivered another approach to print personalized tablets at a temperature lower than prescribed temperatures with required release behavior and can contribute toward the quest of sustainable personalized medication.

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Environmental impacts of conventional and additive manufacturing for the production of Ti-6Al-4V knee implant: a life cycle approach

Cited by 41 publications

References 55 publications

Operating in a Climate Crisis: A State-of-the-Science Review of Life Cycle Assessment within Surgical and Anesthetic Care

Operating in a Climate Crisis: A State-of-the-Science Review of Life Cycle Assessment within Surgical and Anesthetic Care

Integration of Environmental Assessment in Process Engineering of Metal Additive Manufacturing Technology

Investigations of personalized and sustainable approach of oral drug delivery systems through additive manufacturing

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