It is important to remove large environmental noise in superconducting quantum
interference device (SQUID) measurement without magnetic shielding. Active noise control
(ANC) is one of the effective methods to reduce environmental noise. Recently, SQUIDs
have been used in various applications at high frequencies, such as nuclear quadrupole
resonance (NQR). The NQR frequency from explosives is in the range 0.5–5 MHz. In this
case, an NQR sensor is exposed to AM radio frequency interference (RFI). The feasibility
of the ANC system for RFI that used digital signal processing was studied. Our
investigation showed that this digital ANC system can be applied to SQUID measurements
for RFI suppression.