Environmental pH-controlled loading and release of protein on mesoporous hydroxyapatite nanoparticles for bone tissue engineering

Albumin adsorption study onto hydroxyapatite-multiwall carbon nanotube based composites

“…8 the adsorption capacity are shown for 0.5 and 1 g/l initial BSA concentration in 7,5 and 8 pH TRIS based buffers. The reason to study the adsorption at two different pH was motivated by the statement that the lateral repulsion between the protein molecules is more significant at higher solution pH, which also plays a role in lower adsorption [60]. Our findings support the literature data, the adsorption efficiency at pH 7.5 was more efficient than at pH 8, so by increasing the pH value the adsorption efficiency would decrease.…”

Dehydration of Lactic Acid: The State of The Art

“…These solids have rapidly become a subject of interest due to their application in basic or bi‐functional catalysis, particularly the synthesis of heavy alcohols by the Guerbet reaction , Knoevenagel condensation reaction , Michael reaction , or for dehydration , oxidation , and dehydrogenation reactions. This material has also been studied in the field of medicine for applications such as bone integration , dental implants , or vectorization of medicines . HAPs have the general chemical formula Ca 5 (PO 4 ) 3 OH, but are usually described with the formula Ca 10 (PO 4 ) 6 (OH) 2 which actually represents the two molecules in the crystal structure (crystal symmetry, spatial group 6/m) (Fig.…”

Letter to the Editor: Editor's Spotlight/Take 5: Is Single-stage Revision According to a Strict Protocol Effective in Treatment of Chronic Knee Arthroplasty Infections

“…There is some indirect evidence that bone may be more sensitive to pH than has previously been appreciated [7,9]. This notion makes sense since two important enzymes in bone are alkaline phosphatase and acid phosphatase in osteoblasts and osteoclasts (by names alone they are suggestive of possible pH involvement).…”