2015
DOI: 10.1097/cpm.0000000000000095
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Environmental Pollution and the Developing Lung

Abstract: In this review,

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Cited by 9 publications
(5 citation statements)
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References 85 publications
(72 reference statements)
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“…However, a paternal history of TCDD exposure led to a significant reduction in the radial alveolar count, which was normalized in pups whose father received a supplemental fish oil diet preconception (Figure 3C). These results confirm that historical exposure to pollution negatively impacts lung development, however, components of fish oil may mitigate this effect [65,66].…”
Section: Discussionsupporting
confidence: 73%
“…However, a paternal history of TCDD exposure led to a significant reduction in the radial alveolar count, which was normalized in pups whose father received a supplemental fish oil diet preconception (Figure 3C). These results confirm that historical exposure to pollution negatively impacts lung development, however, components of fish oil may mitigate this effect [65,66].…”
Section: Discussionsupporting
confidence: 73%
“…The multiplicative effects of air pollution, from both indoor and outdoor sources and ETS exposures are important particularly as these countries carry the highest burden of child respiratory diseases [96]. ETS combined with other IAP, particularly antenatal exposure, affects lung growth that persists through adulthood [97]. There are numerous by-products of combustion; particulate matter (PM), carbon dioxide (CO 2 ), sulfur dioxide (SO 2 ), nitrogen dioxide (NO 2 ), and volatile organic compounds (VOC) are the most commonly assessed by-products of ETS and other combustions [95,98].…”
Section: Resultsmentioning
confidence: 99%
“…Antenatal exposure to PM 10 was associated with an increased risk of LRTI, as has been previously reported. 10 , 27 , 28 This result might be due to impaired lung growth and increased risk of infection associated with exposure. 29 Furthermore, innate immune responses might be compromised due to impairment of alveolar macrophage function and upregulation of inflammatory responses.…”
Section: Discussionmentioning
confidence: 99%