This paper discusses the contribution of marine sites of outstanding universal value, enlisted as natural and mixed sites in the World Heritage List, to the sustainability of marine resources and protection schemes. Departing from the strict application of the Convention's criteria, the management requirements and good practices will be discussed, with emphasis on the dissemination of the latter in other (non)protected areas as well as its contribution, in terms of the integrity principle to be met, to the expansion of this approach in areas beyond national jurisdiction through the development of synergies with existing and emerging marine environment protection regimes.