Environmentally benign and biocompatible CuO@Si core-shell nanoparticles: As electrochemical l-cysteine sensor, antibacterial and anti-lung cancer agents

Gowtham, Sasikala; Dhivya, Rajakumar; Muthulakshmi, L.; Sureshkumar, S.; Ashraf, M.; Annaraj, Jamespandi; Mayandi, J.; Annaraj, J.; Sagadevan, Suresh

doi:10.1016/j.ceramint.2022.11.182

Cited by 4 publications

(2 citation statements)

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“…Under steady-state conditions, the current method is a simple and sensitive electrochemical detection method [ 4 ]. In an optimized state, applying a potential of −0.0208 V and continuous stirring to promote solution homogenization, the typical amperometric response signals obtained by continuously adding different concentrations of L-cysteine are shown in Figure 9 .…”

Section: Resultsmentioning

confidence: 99%

“…L-cysteine is used for detoxification and regulation of biological oxidative balance, and it is an important biomarker, which can serve as a diagnostic indicator for various diseases. As a therapeutic agent and antioxidant, L-cysteine is widely used in industries such as medicine, food, and cosmetics [ 4 ]. For example, L-cysteine is an amino acid detoxifying agent, which participates in the reduction process of cells and phospholipid metabolism in the liver.…”

Section: Introductionmentioning

confidence: 99%

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Spherical Silver Nanoparticles Located on Reduced Graphene Oxide Nanocomposites as Sensitive Electrochemical Sensors for Detection of L-Cysteine

Hua,

Yao,

Yao

2024

Sensors

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A new, simple, and effective one-step reduction method was applied to prepare a nanocomposite with spherical polycrystalline silver nanoparticles attached to the surface of reduced graphene oxide (Ag@rGO) at room temperature. Equipment such as X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), and Fourier transform infrared spectroscopy (FTIR) was used to characterize the morphology and composition of the Ag@rGO nanocomposite. A novel electrochemical sensor for detecting L-cysteine was proposed based on fixing Ag@rGO onto a glassy carbon electrode. The electrocatalytic behavior of the sensor was studied via cyclic voltammetry and amperometry. The results indicate that due to the synergistic effect of graphene with a large surface area, abundant active sites, and silver nanoparticles with good conductivity and high catalytic activity, Ag@rGO nanocomposites exhibit significant electrocatalytic activity toward L-cysteine. Under optimal conditions, the constructed Ag@rGO electrochemical sensor has a wide detection range of 0.1–470 μM for L-cysteine, low detection limit of 0.057 μM, and high sensitivity of 215.36 nA M−1 cm−2. In addition, the modified electrode exhibits good anti-interference, reproducibility, and stability.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%