2023
DOI: 10.1021/acssensors.3c00209
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Environmentally Resilient Microfluidic Point-of-Care Immunoassay Enables Rapid Diagnosis of Talaromycosis

Abstract: Point-of-care tests (POCTs) are increasingly being used in field settings, particularly outdoors. The performance of current POCTs�most commonly the lateral flow immunoassay�can be adversely affected by ambient temperature and humidity. We developed a self-contained immunoassay platform�the D4 POCT�that can be conducted at the POC by integrating all reagents in a capillary-driven passive microfluidic cassette that minimizes user intervention. The assay can be imaged and analyzed on a portable fluorescence read… Show more

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