Enzymatic degradation, antioxidant and immunoregulatory activities of polysaccharides from brown algae Sargassum fusiforme

Qian, Wenwen; Yang, Siqi; Hu, Shumin; Wang, Xiaoling; Zhu, Yuzhu; Zhou, Tao

doi:10.1007/s11694-020-00776-8

Cited by 32 publications

(19 citation statements)

References 31 publications

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“…In addition, a new study used together pectinase and glucoamylase to degrade the fucoidan from S. fusiforme. In this study, enzymatically degraded S. fusiforme SP showed higher antioxidant activity than the natural S. fusiforme fucoidan (Wen et al 2021) (Table 4). On the other hand, many studies described that degraded or chemically modified SP improved their antioxidant activities compared to the native SP.…”

Section: Antioxidantmentioning

confidence: 59%

Seaweed polysaccharides: Emerging extraction technologies, chemical modifications and bioactive properties

Otero

Carpena

García-Oliveira

et al. 2021

Critical Reviews in Food Science and Nutrition

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Section: Antioxidantmentioning

confidence: 59%

Seaweed polysaccharides: Emerging extraction technologies, chemical modifications and bioactive properties

Otero

Carpena

García-Oliveira

et al. 2021

Critical Reviews in Food Science and Nutrition

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“…The DPPH radical scavenging activity was determined according to the reported method with some modification. [ 15 ] In a nutshell, 1.0 mL of each sample solution (0, 0.2, 0.4, 0.6, 0.8, and 1.0 mg mL ‐1 concentration) was added to 2.0 mL of DPPH solution (0.1 mmol L ‐1 in ethanol). The fluid was kept in dark at room temperature for 30 min after vibration, and the absorbance was measured at 517 nm.…”

Section: Methodsmentioning

confidence: 99%

Extraction, Purification, Characterization, and Bioactive Properties of Polysaccharides from Sphallerocarpus gracilis

Assani

Wang

et al. 2021

Starch Stärke

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Four new polysaccharides, SGP‐1‐4, are isolated and purified from Sphallerocarpus gracilis (S. gracilis) . The monosaccharide analysis revealed that the isolated polysaccharides are composed of different molar ratios of glucose (Glu), galactose (Gal), rhamnose (Rha), mannose (Man), and arabinose (Ara). Congo red test showed that no triple helical structure is detected in SGP‐1‐4. The Zeta potentials of SGP‐1‐4 are negative. The antioxidant activities are evaluated using DPPH and Superoxide radical assays. In vitro antitumor activities are investigated by MTT assay and Calcein‐AM/PI staining confocal imaging. The hypolipidemic activities are measured by the bile‐salt binding capacity in vitro. The results indicated that SGP‐1‐4 possessed significant antioxidant and hypolipidemic abilities. At the concentration of 0.2 mg/mL, the purified polysaccharides possess no significant effects against MGC‐803 (Human gastric cancer cells), A2780 (Human ovarian cancer cells), T24 (Human bladder cancer cells), CNE‐2 (Human nasopharyngeal cancer cells), and 4T1 (Mouse breast cancer cells) tumor cells in vitro. However, the SGP‐2 shows potential as a DOX‐chemotherapy against 4T1 cells, which indicated that SGP‐2 could exert antitumor effects. These findings provide a scientific basis for the further use of S. gracilis polysaccharides as a natural antioxidant, antitumor, and hypolipidemic agent in industry.

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“…Likewise, the results of the investigation of Abhishek et al [ 78 ] demonstrated that methanol solvent was successful in extracting polyphenols from Padina boryana (Ochrophyta, Phaeophyceae), which was strongly correlated with its antioxidant activity. The enzymatically degraded polysaccharide from Sargassum fusiforme brown algae possessed superior antioxidant activity on scavenging HO˙, O 2 ⋅− and DPPH˙ radicals [ 79 ]. Additionally, the freeze-dried samples of the brown alga P. pavonica extracted with ethanol had superior antioxidant activity in hydrogen atom transfer assays of DPPH and ORAC, and with the electron transfer assays of FRAP [ 80 ].…”

Section: Treatment Of Diabetesmentioning

confidence: 99%

Antioxidant and Antidiabetic Activity of Algae

Abo-Shady

Gheda

Ismail

et al. 2023

Life

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Currently, algae arouse a growing interest in the pharmaceutical and cosmetic area due to the fact that they have a great diversity of bioactive compounds with the potential for pharmacological and nutraceutical applications. Due to lifestyle modifications brought on by rapid urbanization, diabetes mellitus, a metabolic illness, is the third largest cause of death globally. The hunt for an efficient natural-based antidiabetic therapy is crucial to battling diabetes and the associated consequences due to the unfavorable side effects of currently available antidiabetic medications. Finding the possible advantages of algae for the control of diabetes is crucial for the creation of natural drugs. Many of algae’s metabolic processes produce bioactive secondary metabolites, which give algae their diverse chemical and biological features. Numerous studies have demonstrated the antioxidant and antidiabetic benefits of algae, mostly by blocking carbohydrate hydrolyzing enzyme activity, such as α-amylase and α-glucosidase. Additionally, bioactive components from algae can lessen diabetic symptoms in vivo. Therefore, the current review concentrates on the role of various secondary bioactive substances found naturally in algae and their potential as antioxidants and antidiabetic materials, as well as the urgent need to apply these substances in the pharmaceutical industry.

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Enzymatic degradation, antioxidant and immunoregulatory activities of polysaccharides from brown algae Sargassum fusiforme

Cited by 32 publications

References 31 publications

Seaweed polysaccharides: Emerging extraction technologies, chemical modifications and bioactive properties

Seaweed polysaccharides: Emerging extraction technologies, chemical modifications and bioactive properties

Extraction, Purification, Characterization, and Bioactive Properties of Polysaccharides from Sphallerocarpus gracilis

Antioxidant and Antidiabetic Activity of Algae

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