Enzymatic Destruction of Film Materials on the Basis of Chitosan in the Presence of Cephalosporin Series Antibiotics

Chernova, V. V.; Tuktarova, I. F.; Shurshina, A. S.; Elinson, Mariya; Kulish, E. I.

doi:10.23939/chcht13.01.071

Cited by 1 publication

(1 citation statement)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The enzyme used was hyaluronidase produced under the Liraza trademark (Microgen CJSC, Moscow, Russia). The principal possibility of the enzymatic destruction of ChTS under the influence of nonspecific enzymes modeling the enzymatic composition of the wound surface was established earlier [22]. The volume of the enzyme preparation solution (0.1 ml) was selected so that the entire surface of the film was covered with the solution.…”

Section: Enzymatic Hydrolysis Of Film Samplesmentioning

confidence: 99%

Experimental evaluation of structure formation in solutions of biopolymer mixtures and prediction of the properties for biomedical materials obtained

et al. 2022

Self Cite

View full text Add to dashboard Cite

The experimental evaluation of structure formation in solutions of individual polymers, as well as in their mixtures with other polymers in order to predict the properties of materials obtained on their basis was the aim of this work. We used chitosan, sodium salt of chitosan succinyl, sodium salt of carboxymethyl cellulose, and polyvinyl alcohol. Distilled water, 1 % acetic acid, and buffer systems based on acetic acid and sodium acetate with pH = 3.80, 4.25, and 4.75 were used as solvents. It was found that the type of aggregates formed in polymer mixtures is determined by the nature of the solvent and the concentration of the polymers in the initial solution. A correlation has been shown between the nature of aggregates formed in solutions and some physicochemical properties of film materials obtained from solutions, namely, the degree of enzymatic hydrolysis, as well as the rate and degree of water vapor sorption by film materials. Thus, the studies carried out show that by varying the nature of the solvent, the concentration and nature of the polymers in the initial solutions, it is possible to control the structure formation in mixed polymer solutions, and, therefore, the properties of the resulting composites.

show abstract

Section: Enzymatic Hydrolysis Of Film Samplesmentioning

confidence: 99%