Enzymatic Synthesis of New Oligosaccharides Using Mannosyltransferases from Candida Species and Their NMR Assignments

Structural Investigation of Cell Wall Mannan Antigen Obtained from Pathogenic Yeast <i>Candida zeylanoides</i>

“…Z was analyzed by means of 2D-HOHAHA (Figure 1). All H-1-H-2 crosspeaks were assigned according to published data [21][22][23][24][25] as shown in Table 2. The quartet signal corresponding peak 1 at 5.4 -5.7 ppm indicates the presence of the phosphorylated oligomannosyl side chain and β-1,2-linked oligomannosyl unit.…”

Enzymes in the Synthesis of Glycoconjugates

“…299 Shibata and Okawa synthesized a series of mannoprotein mimics with R1,2-ManT from C. parapsilosis and R1,6-ManTs from C. albicans. 296 These ManTs were found to be useful for fluorescent protein labeling via addition of azido-modified Man, from GDPazidodeoxymannoses, which can be chemoselectively labeled via Staudinger ligation. 323 4.1.3.…”

Self-recycling and partially conservative replication of mycobacterial methylmannose polysaccharides

“…The α-(1→4) linkage between mannoses found in MMP appears to be extremely rare in nature 13 , which renders the key α-(1→4)-mannosyltransferase a functionally and structurally unique glycosyltransferase. Indeed, mannans from plants show a clear prevalence of β-(1→4) linkages, whereas those from fungi and bacteria essentially contain α-(1→2), α-(1→3) and α-(1→6) linkages and branching 14,15,16 . Also in the mycobacterial mannose polymers phosphatidyl-myo-inositol mannosides (PIM), lipomannan (LM) and lipoarabinomannan (LAM), mannose units are essentially connected through α-(1→6) and α-(1→2) glycosidic bonds 7 .…”