Enzyme Free Detection of Glucose Using MgO Nanocubes Based Extended Gate N-channel MOSFET

Abstract

MgO nanocubes were used as a sensing electrode material for detection of glucose in the extended gate field effect transistor (EGFET) configuration. MgO nanocubes were prepared by thermal CVD approach. Morphology and elemental composition of as-prepared MgO nanocubes were obtained using the scanning electron microscope (SEM) along with EDS. The sensing electrode was prepared by coating MgO nanocubes over the copper foil by doctor blade method and it was tested with various concentrations of glucose in Phosphate Buffer Saline (PBS) buffer solution. The MgO nanocubes coated electrode showed linear response for glucose concentrations from 1.6 mM to 25.6 mM. The sensitivity was calculated as 0.12 |aA/mM.cm2.

Magnesium Oxide (MgO) Nanoparticles: Synthetic Strategies and Biomedical Applications

“…A glucose sensor utilizing a non-enzymatic setup employing magnesium oxide nanocubes as the basis was developed and studied by Prasanna and colleagues [206]. Throughout experimental studies, the sensing electrode demonstrated a notable shift in drain current concerning glucose concentration, ranging from 1.6 mM to 25.6 mM.…”