Enzyme-photo-coupled catalytic systems

Abstract

Recent advances in enzyme-photo-coupled catalytic systems are reviewed and highlighted from the perspective of system engineering.

Synthesis of Enantiopure Sulfoxides by Concurrent Photocatalytic Oxidation and Biocatalytic Reduction

“…Photobiocatalytic strategies that have gained considerable attention in the past years include the use of natural photo‐enzymes, [4] and the application of promiscuous reactions of enzymes under illumination, [5, 6] but also the use of photocatalytic–biocatalytic cascades [6–8] as well as photocatalytic cofactor recycling systems [9] . However, to unlock their full reactivity, photo‐ and biocatalysts usually require diverging reaction conditions: [3, 4, 6, 8, 10, 11] While enzymatic reactions are best performed in water, most photocatalysts require organic solvents. Furthermore, organocatalytic reactions are often accelerated at high temperatures that are harmful for enzymes.…”

Confining enzymes in porous organic frameworks: from synthetic strategy and characterization to healthcare applications

“…147 In addition, its pyrene core endowed HOF-102 with high photochemical activity, and therefore it may provide an avenue for the rational organization of enzymatic photocatalysis in further research. 148 3.2.2 Hierarchical pores. Engineering COFs or HOFs with uniformly large pores shows huge potential for stabilizing encased enzymes against external stimuli and may offer extraordinary enhancement in catalytic activities by further chemical modulation of the pore environment.…”

Bioinspired Metalation of the Metal‐Organic Framework MIL‐125‐NH2 for Photocatalytic NADH Regeneration and Gas‐Liquid‐Solid Three‐Phase Enzymatic CO2 Reduction

“…Especially, by further immobilizing the enzyme, constructing the recyclable synthetic materials-enzyme hybrids as the semi-artificial photosynthetic system for CO 2 reduction is very promising for sustained commercial applications in solar energy conversion. [16][17][18] Photocatalytic NADH regeneration usually occurs in the presence of photocatalysts as well as homogeneous metal complex (such as [Cp*Rh(bpy)H 2 O] 2 + ), which act as the electron and proton mediator. [19][20][21][22][23][24][25] Previously, most of the photoinduced electrons were transferred from the heterogeneous semiconductor particles to the homogeneous Rh complex to accomplish the first step of the photocatalytic NADH regeneration, which could pose severe electron transfer loss.…”

“…Inspired by natural photosynthesis, the coupling of photocatalytic NADH regeneration with the bioenzymatic CO 2 reduction could serve the purpose of fine chemicals production utilizing solar energy. Especially, by further immobilizing the enzyme, constructing the recyclable synthetic materials‐enzyme hybrids as the semi‐artificial photosynthetic system for CO 2 reduction is very promising for sustained commercial applications in solar energy conversion [16‐18] …”