“…ILs have unique properties that make them useful as green solvents for many biocatalytic reactions [8,9]. They are non-volatile, non-flammable, and have excellent chemical and thermal stability, which can provide enzymes with excellent levels of activity, stability, and stereoselectivity [10,11]. For enzyme catalysis, the activity and stability of enzymes are closely related to the physicalchemical properties of ILs (e.g., polarity, viscosity, hydrogen bond basicity, hydrophobicity and anion concentration) [12].…”