Enzymes and Targeted Activation of Prodrugs

Yang, Yanhui; Chen, Yu; Aloysius, Herve; Inoyama, Daigo

doi:10.1002/9781118739907.ch5

Enzyme Technologies 2013

DOI: 10.1002/9781118739907.ch5

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Enzymes and Targeted Activation of Prodrugs

Yanhui Yang

Yu Chen

Herve Aloysius

et al.

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2019

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Origination Progress and Utility of Selective Estrogen Receptor Modulators in Clinical Practice as an Efficient Substitute of Estrogen for Treating Hormone Dependent Issues

Kulshrestha

Pandey

2019

ajomc

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The discovery, development and utility of selective estrogen receptor modulators (SERMs) are presented in this study. As per literature review SERMs used in the treatment of estrogen hormone responsive diseases like osteoporosis, Alzheimer, angiogenesis, hyperlipidemia, coronary heart disease, atherosclerosis, endometriosis, breast cancer, post-menopausal depression, dysfunctional uterine bleeding, gynacomastia, Albright syndrome, ovarian cancer, dyspareunia, cyclical mastalgia, hypogondism and induced ovulation in sub-fertile woman, etc. Basically world wide a large no. compounds available those function as SERMs successfully or under different phase clinical trials or discontinued because of unwanted side effects during clinical trials. This work describes the specific reference compounds which have created a substitute of estrogen for treating hormone dependent issues.

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Origination Progress and Utility of Selective Estrogen Receptor Modulators in Clinical Practice as an Efficient Substitute of Estrogen for Treating Hormone Dependent Issues

Kulshrestha

Pandey

2019

ajomc

View full text Add to dashboard Cite

show abstract

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Enzymes and Targeted Activation of Prodrugs

Cited by 1 publication

References 243 publications

Origination Progress and Utility of Selective Estrogen Receptor Modulators in Clinical Practice as an Efficient Substitute of Estrogen for Treating Hormone Dependent Issues

Origination Progress and Utility of Selective Estrogen Receptor Modulators in Clinical Practice as an Efficient Substitute of Estrogen for Treating Hormone Dependent Issues

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