Enzymes as denture cleansers

Abstract

– It was the purpose of the study to test the efficiency of dextranase., mutanase, and protease in removing denture plaque. The study group comprised 100 denture‐wearers with denture stomatitis. The enzymes were dispensed as dissolvent tablets either in pure or in mixed preparations. Placebo tablets and Steradent®. a commercial denture cleanser, were used as control tablets. The following parameters were studied: the amount of denture plaque., the degree of palatal erythema, and the concentration of yeast cells and inflammatory cells in mucosal and denture smears. The study was designed and carried out as a double‐blind study. The dissolvent tablets containing the enzymes in mixed preparations were more effective than the tablets containing the pure enzymes, the placebo tablets, or the Steradent® tablets. The beneficial effect of the mixed enzyme preparations included a significant reduction of the amount of denture plaque and an improvement of the clinical condition of the palatal mucosa.

Interventions for the Management of Denture Stomatitis: A Systematic Review and Meta‐Analysis

“…Of the 35 included trials, 11 did not have data to be entered in the meta‐analysis because they presented the results only in figures or graphs or because the data were not usable for statistical analysis …”

“…Articles that did not mention any blinding of participants or personnel or assessment of outcome or that clearly stated that they were not blinded were rated as being at high risk of bias. Eight studies were blinded to participants, personnel, and outcome assessment …”

Analysis of prompt fission neutrons in235U(nth,f) and fission fragment distributions for the thermal neutron induced fission of234U

“…[6]. The conservation of mass and momentum provides the means of calculating the pre-fission neutron emission distributions.…”

Comparative Studies on the Induction of Trichoderma harzianum Mutanase by α-(1→3)-Glucan-Rich Fruiting Bodies and Mycelia of Laetiporus sulphureus

“…The mutan-degrading enzyme has a high potential as a caries preventive agent, due to its ability to solubilize mutans present in dental plaque as well as denture plaque [1–3]. As an active ingredient in dentifrice preparations and chewing gum, mutanase could become a useful supplement to mechanical cleaning of teeth and dentures with a toothbrush, dental sticks, and dental floss.…”