Enzymhistochemische Untersuchungen an reifen menschlichen Placentazotten

Kaufmann, Peter; Stark, J.

doi:10.1007/bf00305702

Cited by 33 publications

(3 citation statements)

References 18 publications

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“…This assumption is in agreement with the finding that the sinusoids are regularly situated in contiguity with the epithelial plates (Boyd & Hamilton, 1970;Nikolov & Schiebler, 1973Schiebler & Kaufmann, 1981). These plates are thought to represent areas of maximal diffusional exchange (Amstutz, 1960;Kaufmann et al, 1974).…”

Section: Functionmentioning

confidence: 99%

Architecture of Normal Villous Trees

Benirschke

Burton

Baergen

2012

Pathology of the Human Placenta

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Section: Functionmentioning

confidence: 99%

Architecture of Normal Villous Trees

Benirschke

Burton

Baergen

2012

Pathology of the Human Placenta

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“…On the other hand, ultrastructural and enzyme histochemical studies have demonstrated distinct regions within the syncytiotrophoblast showing signs of ageing or degeneration such as loss of polyribosomes, degranulation of endoplasmic reticulum, condensation of chromatin and loss of enzymes of energy metabolism (Kaufmann, 1972;Kaufmann and Stark, 1972;Martin and Spicer, 1973). The data in these old descriptive papers suggested that such ageing areas of the syncytiotrophoblast were preferably involved in fusion.…”

Section: Introductionmentioning

confidence: 99%

Syncytin: the major regulator of trophoblast fusion? Recent developments and hypotheses on its action

Pötgens¹,

Drewlo²,

Kokozidou³

et al. 2004

Human Reproduction Update

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108

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Syncytin is a membrane protein derived from the envelope gene of an endogenous retrovirus of the HERV-W family. The gene appears to be almost exclusively expressed in placenta; the protein was found in particular in syncytiotrophoblast. After transfection into various cell types it has proven to be a very fusogenic protein, inducing the formation of syncytia. Therefore, the question rises as to whether syncytin is responsible for the fusion process of villous cytotrophoblast into syncytiotrophoblast in vivo. If so, how is this fusion process regulated if syncytin is found all over the syncytiotrophoblast? Can this process be regulated through local or temporal changes in syncytin expression, or is syncytin merely one factor in a cascade of events leading to fusion limited at some other level? This review will try to summarize the published data on the regulation of fusion in trophoblast models as well as on the localization and regulation of syncytin expression and of its presumed receptors. Assuming that syncytin is the key factor inducing trophoblast fusion, a number of models will be presented by which syncytin and/or its receptors might regulate this process. In some of the hypotheses proposed, local coexpression of syncytin and receptor, leading to blocking of one factor by the other, is of functional relevance.

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“…Ιστοχημικώς παρουσιάζουν έντονη αντίδραση στην 17βυδοξυστεροειδοδευδρογενάση. Η παρουσία αυτών των ζωνών δικαιολογεί την αυξημένη συγκέντρωση της 17β-υδοξυστεροειδοδευδρογενάσης στο μητρικό αίμα και της οιστριόλης στα ούρα της μητέρας 13. 3.…”

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Λειτουργική Μορφολογία Των Ενδοθηλιακών Κυτταρικών Συνάψεων Και Διαπερατότητα Του Πλακούντα

Μάινας¹

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Σκοπός της εργασίας αυτής είναι η μελέτη της διαπερατότητας του εμβρυϊκού και του πλακουντιακού αμνίου στους μύες . Ως ίχνος υλικό χρησιμοποιήθηκαν κοκκία άνθρακα σε εναιώρημα που εγχύθηκε στην αμνιακή κοιλότητα των μυών 4 ημέρες πριν από τον τοκετό. Ακολούθως τα ιστοτεμάχια εξετάσθηκαν τόσο στο οπτικό όσο και στο ηλεκτρονικό μικροσκόπιο. Παρατηρήθηκαν δύο τύποι επιθηλιακών κυττάρων ειδικών για κάθε μοίρα του αμνίου. Η μεταφορά των κοκκίων του άνθρακα γίνεται διακυτταρίως και όχι παρακυττάρια μέσω πόρων-κενοτοπίων. Συμπερασματικά το επιθήλιο του αμνίου λειτουργεί διαφορετικά ανάλογα με την εντόπισή του αποτελώντας έναν ακόμη μέσο ανταλλαγής ουσιών .

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Enzymhistochemische Untersuchungen an reifen menschlichen Placentazotten

Cited by 33 publications

References 18 publications

Architecture of Normal Villous Trees

Architecture of Normal Villous Trees

Syncytin: the major regulator of trophoblast fusion? Recent developments and hypotheses on its action

Λειτουργική Μορφολογία Των Ενδοθηλιακών Κυτταρικών Συνάψεων Και Διαπερατότητα Του Πλακούντα

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