Eosinophilic Cholangiopathy Mimicking Cholangiocarcinoma: Case Report

Sohail, Maaz; Hammami, Muhammad B.; Charles, C

doi:10.14309/00000434-201810001-01448

Cited by 1 publication

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“…Furthermore, there has been no expert consensus on the appropriate treatment for EC and current treatment modalities are based on case reports and case-based experiences [6]. In our case [14], the patient had evidence of wall thickening, stenosis of the biliary system, and histopathological evidence of eosinophilic infiltration supporting aspects of the diagnostic criteria proposed by Matsumoto et al The reversibility of biliary abnormalities was unclear in our case and was difficult to assess, however, it cannot be excluded and should be a point of emphasis for future research.…”

Section: Discussionmentioning

confidence: 99%

A Challenging Diagnosis of Eosinophilic Cholangitis Requiring Resection of Extrahepatic Bile Ducts

Hammami¹,

Ohanisian²,

Kaur³

et al. 2019

Cureus

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Eosinophilic cholangitis (EC) is a rare benign disease characterized by transmural eosinophilic infiltration of the biliary tree that may result in biliary stricture and obstructive jaundice. The pathophysiology remains unknown but is theorized to involve an allergic mechanism. EC is diagnostically challenging as it may mimic cholangiocarcinoma (CCA) clinically and radiographically and involves a broad differential diagnosis including benign and malignant pathologies. In addition to tumor markers, ultrasonography, contrast-enhanced computed tomography (CT), and magnetic resonance cholangiopancreatography (MRCP), proper evaluation of malignant processes may need biopsy through endoscopic retrograde cholangiopancreatography (ERCP) and surgical exploration. We present the case of a 47-year-old female diagnosed with EC upon exploratory laparotomy.

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Section: Discussionmentioning

confidence: 99%