Eosinophilic Cholecystitis

Eosinophilic Cholecystitis as an Atypical Etiology of Biliary Colic: A Case Report and Review of the Literature

“…The nature of this pathology remains uncertain, since although some authors propose the association of EC with allergies, including penicillin, as in the case of our patient [ 5 , 6 ], other authors haven't found any association [ 4 ], in the case of our patient, there was only a history of allergy to penicillin. In our case, maybe liver cirrhosis could be related, however there are no associations reported in the literature.…”

“…EC is usually a benign condition; in those patients who only present inflammation of the gallbladder, it resolves with the surgical intervention "cholecystectomy" [5][6][7]. However, it will be necessary to look for some other associated condition intentionally to treat it.…”

“…Clinically, EC is indistinguishable from other types of cholecystitis [4,5], the diagnosis is made with the pathology study in which the vesicular wall is infiltrated in >90% by eosinophils [5][6][7]. The course of the disease is determined by diseases associated with EC, such as eosinophilic granulomatosis, eosinophilic ascites, or parasitosis; because of this, it's important to check for any other disorders that may be related and treat them if necessary [5,6]. However, most of the time it takes a benign course.…”

“…Acute cholecystitis has a wide range of etiologies; among them, lithiasis accounts for 90% to 95% of cases [ 1 , 2 ]. Other types include acalculous cholecystitis, the less common emphysematous cholecystitis [ 3 ] and the even rarer eosinophilic cholecystitis (EC), which was first described in the French literature [ 4 ] by Albot in 1949 [ 5 , 6 ].…”

“…More recently, Gutierrez-Moreno et al reported a prevalence of 0.16% [ 6 ] in the Mexican population. Hypersensitivity or allergy to drugs such as penicillins, immunosuppression, and parasitosis, among others, have been proposed as associated risk factors [ 5 , 6 ]. On the other hand, some case series, such as the one reported by Khan et al did not find any association with the previously described factors in their 22 patients diagnosed with EC [ 4 ], so the etiology still remains uncertain.…”