Eosinophilic colitis: an infrequent disease with difficult diagnose

Abstract

Eosinophilic colitis (EC) is a rare entity. It is part of eosinophilic gastroenteritis, a rare inflammatory disorder characterised by eosinophilic infiltration of tissues that can affect any segment of the digestive tract. The diagnosis is established by the presence of an increased eosinophilic infiltrate in the colon wall in symptomatic patients. There is no characteristic clinical picture of EC. It can be associated with abdominal pain, changes in bowel movements, diarrhoea and rectal bleeding. Biopsies are mandatory if EC is suspected and despite visualising a normal mucosa. Although there are no protocol guidelines in this regard, steroid treatment is the first option in controlling the disease. Increasing the knowledge of clinicians and pathologists of this disorder and the recording its real incidence and population impact, could improve the understanding and treatment of the disease.

Colitis eosinofílica subserosa: reporte de caso en un hospital privado de Lima - Perú

“…Este último esquema es el que se indicó en el paciente, con el cual llegó a tener remisión de síntomas, así como la normalización de la eosinofilia luego de 2 semanas de inducción con prednisona a 40 mg diarios, y posteriormente con retiro progresivo, teniendo nuevamente un recuento de eosinófilos normales a las 4 semanas y ausencia de la ascitis. Esta forma de tratamiento se indicó en algunos casos, tal como en el descrito por Yep Gamarra y colaboradores (21) , que tuvo una presentación de gastroenteritis con ascitis; en el de Sánchez y colaboradores (22) y como en el caso presentado por Páramo-Zunzunegui y colaboradores (23) , todos con remisión clínica exitosa.…”

Eosinophilic ulcerative colitis- case report and literaturereview

“…Non-IgE dependent Th2 allergy tests can also be performed, but have the same limitations as AST and RAST. [1][2][3][4][5][6] Imaging studies are nonspecific regardless of age group, but it is important to have them on hand. In general, ultrasound, CT, radiography or barium fluoroscopic studies may show intestinal wall thickening, ascites, edema, intestinal wall nodularity, the spiral spring sign (because of intestinal wall stratification) and/or the «araneide-limb-like» sign mainly in the ascending and transverse colon, this last sign occurs because of the prominence of contrast on CT at these site.…”

“…5 Because of the irregular distribution and the nonspecific findings, multiple biopsies in different locations are necessary for a more accurate result. [1][2][3][4][5][6]…”