Eosinophilic Colitis, an Uncommon Cause of Diarrhea: Case Report and Literature Review

Abstract

Eosinophilic colitis and hypereosinophilic syndrome with colic involvement are rare diagnosis that are characterized by wide-ranging gastrointestinal symptoms and idiopathic infiltration of eosinophils in the colon. The diagnostic workup is challenging since there are no standardized criteria. We report a case of a man admitted to the hospital with a history of nonbloody chronic diarrhea. The detailed workup demonstrated blood eosinophilia, and the colonic biopsies revealed extensive eosinophilic infiltration. He was treated with steroids with clinical and analytical improvement. Due to relapsing colitis after therapy withdrawal, he was chronically medicated with 10 mg of prednisolone with ultimate symptom control. This case report describes the diagnostic workup and highlights the most important features of this often underdiagnosed entity.

A 7-year-old child presented with eosinophilic cystitis as the manifestation of hypereosinophilic syndrome: A case report

“…Overproduction of eosinophil causes the release of toxic granules products, lipid mediators such as sulfidopeptid leukot- rienes, and cytokines like GM_CSF. Cytokines and chemokines, such as interleukins IL-5, IL-3, and granulocyte-macrophage colony-stimulating factor (GM-CSF) can induce degranulation and activation of Eos and organ damage [16][17][18].…”

Restorative Treatment Considerations for Black Triangle: A Case Series

“…Veneer preparation is minimal and has the benefit of bonding by remaining in enamel. It derives its strength from the enamel bonding and thus becomes a monobloc along with the tooth 19 and is thus unsuitable for a tooth that has been extensively restored. Due to the need for bonding, the margin should be at the equigingival margin for easy moisture control and aesthetic purposes.…”

“…This includes patients' aesthetic concern, assessment of the static and dynamic occlusion, presence or absence of parafunctional habits, and assessment of the remaining tooth structure while also considering the expertise of the clinician and the technician. 19 These assessments will determine the materials of choice, margin placement, and types of indirect restorations suitable for each case.…”