Eosinophilic endomyocardial fibrosis and strongyloides stercoralis: A case report

Alizadeh-Sani, Zahra; Vakili-Zarch, Anoushiravan; Kiavar, Majid; Bahadorian, Behdad; Nabavi, Abas

doi:10.5812/cardiovascmed.9370

Cited by 8 publications

(3 citation statements)

References 4 publications

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“…A total of 17 cases of EA, 16 associated with parasitic infection and 1 with fungal infection, were identified. Six types of parasites were associated with EA development: Toxocariasis (6 cases) [86][87][88][89][90][91], Strongyloides stercoralis (5 cases) [92][93][94][95][96], Giardia (1 case) [97], Trichuris trichiura (1 case) [98], Ascaris (1 case) [99], Enterobius vermicularis (1 case) [100]. In one patient parasitic etiology [101] was assumed based on therapeutic response to Albendazole administration.…”

Section: Parasitic and Fungal Infectionsmentioning

confidence: 99%

Causes of eosinophilic ascites – A systematic review

Pinte

Băicuș

2019

Romanian Journal of Internal Medicine

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Background. In the last years an uprising interest for a relatively unknown entity, eosinophilic ascites (EA), has been recorded. Our aim is to investigate the potential causes of EA development, as well as clinical, laboratory, endoscopic and radiologic features, management and outcome in these patients. Methods. The following research was performed on PubMed (MEDLINE) database using the medical subject headings [Mesh] terms “Ascites” AND “Eosinophils”. Results. A total of 284 results, dating from 1962 onwards, were found and abstracts were examined. 131 papers were excluded and the remaining 153 publications, consisting in case reports and series of cases, were analyzed. From 171 patients with EA, 127 subjects (74%) had EGE, 17 (10%) parasitic and fungal infections, 11(7%) Hypereosinophilic syndrome and 16 patients (9%) less common diseases (eosinophilic pancreatitis, chronic eosinophilic leukemia, myelofibrosis, T-cell lymphoma, Churg Strauss Syndrome, Systemic lupus erythematosus, Familial paroxysmal polyserositis and Ménétrier’s disease). High eosinophil blood count and IgE levels as well as gastrointestinal symptoms are frequent. The diagnosis is based on ascitic fluid analysis, imaging and endoscopic biopsies. Therapy with corticosteroids results in resolution of eosinophilic ascites in almost all patients. Conclusion. In most cases, in the absence of allergy, parasitic infections, malignancy, hematological disorders, peritoneal tuberculosis, inflammatory bowel disease or autoimmune disease, EA develops as a manifestation of eosinophilic gastroenteritis.

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Section: Parasitic and Fungal Infectionsmentioning

confidence: 99%

Causes of eosinophilic ascites – A systematic review

Pinte

Băicuș

2019

Romanian Journal of Internal Medicine

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“…Endomyocardial fibrosis and Löffler endocarditis have also been described in the literature although very rarely (Murali et al 2010;Alizadeh-Sani et al 2013;Sarangi et al 2013;Thaden et al 2013;Nolan et al 2013). Afflicted patients were otherwise immunocompetent individuals who presented with heart failure symptoms as the most prominent manifestations of disease.…”

Section: Cardiac Diseasementioning

confidence: 99%

Strongyloides stercoralis hyperinfection syndrome: a deeper understanding of a neglected disease

Vasquez-Rios

Pineda-Reyes

et al. 2019

J Parasit Dis

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Strongyloides stercoralis hyperinfection syndrome (SHS) is a life-threatening condition that warrants early detection and management. We describe the pathogenesis, organ-specific clinical manifestations, and risk factors associated to this condition. A comprehensive review of the literature was conducted in PubMed, LILACS, EBSCO and SciELO by using the keywords: ''hyperinfection syndrome''; ''Strongyloides stercoralis''; ''disseminated strongyloidiasis''; ''systemic strongyloidiasis'', ''pathogenesis'' and ''pathophysiology''. Relevant articles on this topic were evaluated and included by consensus. Also, a secondary search of the literature was performed. Articles in English and Spanish language were included. SHS has been described in tropical and subtropical regions. However, there is growing evidence of cases detected in developed countries favored by increasing migration and the advance in immunosuppressive therapies for oncologic and inflammatory diseases. SHS is characterized by massive multiplication of larvae, typically in immunocompromised hosts. Clinical manifestations vary according to the organ involved and include diarrhea, intestinal bleeding, alveolar hemorrhages, heart failure, jaundice, bacteremia among others. Despite advances in the understanding of this condition, fatality rates are near 90%. Clinicians should consider SHS in the differential diagnosis of acutely ill patients with multiple organ damage and epidemiological risk factors. Adverse outcomes are common, especially with delayed anti-parasitic treatment.

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“…Cardiac involvement in Strongyloidiasis is not that common. Pathologically, it is characterized by restrictive CM resulting from toxic damage produced by activated eosinophils and endomyocardial fibrosis with obliteration of the RV and LV [140][141][142]. Clinical manifestation of Strongyloidiasis vary based on the acuity of the infection and the underlying host response.…”

Section: Strongyloides (Strongyloidiasis)mentioning

confidence: 99%

Parasitic (Helminthic) cardiomyopathy: A review and pooled analysis of pathophysiology, diagnosis and clinical management

Albakri¹

2019

Med Clin Arch

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Neglected tropical diseases form an important component of the burden of cardiac disease in resource-constrained countries. Some diseases resulting from infection by helminthic parasites such as endomyocardial fibrosis, schistosomiasis and hookworm infections are part of the neglected tropical diseases. The neglect has contributed to the under-appreciation and under-research of helminthic cardiac diseases. In contrast, infections by helminthic parasites are prevalent in resource-constrained countries and are among the leading aetiology of cardiac diseases including cardiomyopathy often associated with an ominous prognosis. Infection by a wide variety of helminth parasites, more commonly Trichinella, Taenia solium, Echinococcus, Schistosoma, Toxocara and Ascaris, and less commonly, Heterophyes, Paragonimus, Strongyloides and Dirofilaria Immitis can result in myocardial injury ultimately progressing to cardiomyopathy. However, data on epidemiology, presentation, diagnosis and management of helminthic cardiomyopathy are few and disparate effectively undermining exact understanding. Moreover, expert guidelines specific to the diagnosis and management of helminthic cardiac diseases are also conspicuously lacking. Current clinical practices on management of helminthic cardiomyopathy appear to depend on health centre experience. This paper aims to provide a broadened view of the clinical status of helminthic cardiomyopathy by reviewing published evidence with a particular focus on the causative helminthic parasites, pathophysiology, diagnosis and clinical management.

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Eosinophilic endomyocardial fibrosis and strongyloides stercoralis: A case report

Cited by 8 publications

References 4 publications

Causes of eosinophilic ascites – A systematic review

Causes of eosinophilic ascites – A systematic review

Strongyloides stercoralis hyperinfection syndrome: a deeper understanding of a neglected disease

Parasitic (Helminthic) cardiomyopathy: A review and pooled analysis of pathophysiology, diagnosis and clinical management

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