Eosinophilic granulomatosis with polyangiitis presenting with a vesicovaginal fistula

Famokunwa, Bamidele; Ockrim, Jeremy; Manson, Jessica

doi:10.1093/rheumatology/kew458

Cited by 2 publications

(2 citation statements)

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“…An attempt at surgical closure of the fistula failed, and a flare of the EGPA subsequent to surgical intervention resulted in rapid deterioration of her condition with acute renal failure and sepsis. Administration of methylprednisolone resulted in improvement in her pain and normalization of CRP, allowing sufficient conditions in which an ileal conduit diversion was possible [55].…”

Section: Eosinophilic Granulomatosis With Polyangiitis (Egpa)mentioning

confidence: 97%

Urological Manifestations of the Systemic Vasculitides—A Scoping Review

Nowak

Krajewski

Krajewska

et al. 2021

Uro

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Background: Vasculitides are specific inflammations of the blood vessel wall that can take place in any organ system of the human body. They may occur as a primary process (primary systemic vasculitides, PSV) or may be secondary to another underlying disease. In general, in association with the specific type of vasculitis, affected vessels vary in size, type, and location. In the following scoping review, we present clinical characteristics and manifestations of PSV with reference to the genitourinary system. Materials and methods: A non-systematic search of the relevant literature was conducted using three electronic databases (PubMed, Embase, and Web of Science) up to 29 October 2021. Results: Urogenital manifestations of PSV are infrequent, with the most commonly reported findings as prostatic or testicular involvements. However, almost all other organs of the genitourinary system can be affected. Conclusions: Because of the clinical heterogeneity and non-specific symptoms, the proper diagnosis of PSV is often delayed and constricted. Fast identification of urological manifestations of vasculitides is essential in implementing appropriate therapy and avoiding unnecessary, harmful, and invasive surgery.

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Section: Eosinophilic Granulomatosis With Polyangiitis (Egpa)mentioning

confidence: 97%

Urological Manifestations of the Systemic Vasculitides—A Scoping Review

Nowak

Krajewski

Krajewska

et al. 2021

Uro

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“…The pathological diagnosis of vasculitis in patients with GPA, microscopic polyangiitis (MPA), or eosinophilic granulomatosis with polyangiitis (EGPA, Chug-Strauss syndrome) is difficult, sometimes not possible. We excluded five patients with genital tract involvement from our review, one with MPA and four with EGPA [7][8][9][10][11].…”

Section: Main Findingsmentioning

confidence: 99%

Granulomatosis with Polyangiitis-Mimicking Advanced Gynecological Cancer: A Case Report and Systematic Review of the Literature

Pereira

Magrina

Magtibay

et al. 2022

JPM

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(1) Background: Granulomatosis with polyangiitis (GPA) is a necrotizing vasculitis that mimics gynecologic cancer. In GPA patients, the genitourinary system is affected in <1%. The objective of the study was to provide a systematic review of the literature of GPA patients with gynecological involvement. (2) Methods: PubMed and Embase were searched from inception to July 2021 for GPA patients with gynecological involvement Medical Subject Headings (MeSH) and free-text terms. Exclusion criteria were other language, review articles, pregnancy, fertility, or male patients. Data were extracted on clinical evolution, symptoms, examinations findings, diagnosis delay, treatment, outcome, patient status, and follow-up. (3) Results: Seventeen studies included data from patients with GPA and primary or relapsed gynecological involvement. 68% of the authors of this review thought the patient had cancer. The main gynecological symptom is bleeding, but exclusive gynecologic symptomatology is rare (ENT: 63%, lungs: 44%, kidneys-urinary tract: 53%). GPA could affect all areas of the genital tract, but the most frequent location is the uterine cervix. Medical treatment for GPA is effective. (4) Conclusions: GPA of the female genital tract must be considered when biopsies of an ulcerated malignant-appearing cervical or vaginal mass are negative for malignancy even when they are unspecific. Rheumatology consultation is indicated.

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Eosinophilic granulomatosis with polyangiitis presenting with a vesicovaginal fistula

Cited by 2 publications

References 0 publications

Urological Manifestations of the Systemic Vasculitides—A Scoping Review

Urological Manifestations of the Systemic Vasculitides—A Scoping Review

Granulomatosis with Polyangiitis-Mimicking Advanced Gynecological Cancer: A Case Report and Systematic Review of the Literature

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