Eosinophilic Pneumonia as an Initial Manifestation of Rheumatoid Arthritis

Norman, Daniel; Piecyk, Monica; Roberts, David H.

doi:10.1378/chest.126.3.993

Cited by 25 publications

(12 citation statements)

References 6 publications

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“…However, it may overlap with COP, as in the figures of histopathological features reported in the series by CARRINGTON et al [135], where typical buds of granulation tissue in addition to eosinophilic pneumonia are seen. Other cases of overlap of organising pneumonia and chronic eosinophilic pneumonia (idiopathic or not) have been reported [136][137][138][139][140]. Furthermore, increased level of eosinophils in BAL may be found in some patients with COP.…”

Section: Typical Copmentioning

confidence: 99%

Cryptogenic organising pneumonia

Jf¹

2006

Eur Respir J

484

466

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Organising pneumonia is defined histopathologically by intra-alveolar buds of granulation tissue, consisting of intermixed myofibroblasts and connective tissue. Although nonspecific, this histopathological pattern, together with characteristic clinical and imaging features, defines cryptogenic organising pneumonia when no cause or peculiar underlying context is found. Rapid clinical and imaging improvement is obtained with corticosteroid treatment, but relapses are common after stopping treatment.

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Section: Typical Copmentioning

confidence: 99%

Cryptogenic organising pneumonia

Jf¹

2006

Eur Respir J

484

466

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“…Other findings that may be seen are increased histiocytes, eosinophilic and lymphocytic infiltration of airspaces, eosinophilic abscesses, granulomas, and areas of fibrosis. In rheumatoid arthritis, eosinophilic pneumonias have been described as an acute 35 or chronic 36 -38 phenomenon in which the patients developed increased respiratory symptoms and arthralgias. The reported cases had peripheral eosinophilia, positive rheumatoid factor, and were ANA-negative.…”

Section: Discussionmentioning

confidence: 99%

“…The reported cases had peripheral eosinophilia, positive rheumatoid factor, and were ANA-negative. [35][36][37][38] Radiologic studies showed peripheral infiltrates. 35,37,38 Histologic examination showed interstitial and intra-alveolar eosinophilia and organizing pneumonia.…”

Section: Discussionmentioning

confidence: 99%

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Acute Eosinophilic Pneumonia

Contreras

Rossi

Schwartz

2007

Pathology Case Reviews

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Acute eosinophilic pneumonia is an acute febrile illness of unknown etiology without other systemic manifestations. It can present itself as an acute respiratory distress-like syndrome, which responds to corticosteroid therapy and does not relapse after discontinuation of therapy. Here we present the case of a 51-year-old man with borderline hypertension who presented to our institution with a 2-week history of sinus congestion and gradual onset of shortness of breath. Acute eosinophilic pneumonia was diagnosed on wedge biopsies and improved with corticosteroid treatment. This case report focuses on acute eosinophilic pneumonia and reviews the clinical, radiologic, and morphologic findings, with an emphasis on differential diagnosis.

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“…EP associated with RA is very rare; only seven case reports have been published since the first report was published in 1980 (8)(9)(10)(11)(12)(13)(14). However, the case reported by Payne and Connellan in 1980 was diagnosed based on only radiological findings without histological or BAL findings, therefore the diagnosis of EP seems uncertain (14).…”

Section: It Is Well Known That Ra Complicates Lung Diseases and Some mentioning

confidence: 99%