2018
DOI: 10.1016/s0167-8140(18)31477-4
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EP-1167: Indications for external beam radiotherapy in differentiated thyroid carcinoma: an expert consensus

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“…Although prior retrospective studies have demonstrated survival benefits of adjuvant EBRT (11), its selective use is suggested only in certain DTC patients (those over age 60 years with initial extrathyroidal extension but without gross residual disease; or younger patients with T4b/extensive T4a disease and poor histologic features) (12,13). An expert consensus from the 37th Annual Conference of European Society Radiation Oncology also stated the relevant indications for EBRT in DTC: pT4 tumors with a grossly positive margin (R2) and low/no RAI uptake; or surgically unresectable loco-regional recurrences with low/no RAI uptake (14). The role of EBRT in the postoperative setting of DTC remains controversial in the absence of prospective randomized clinical trials (15,16).…”
Section: Discussionmentioning
confidence: 99%
“…Although prior retrospective studies have demonstrated survival benefits of adjuvant EBRT (11), its selective use is suggested only in certain DTC patients (those over age 60 years with initial extrathyroidal extension but without gross residual disease; or younger patients with T4b/extensive T4a disease and poor histologic features) (12,13). An expert consensus from the 37th Annual Conference of European Society Radiation Oncology also stated the relevant indications for EBRT in DTC: pT4 tumors with a grossly positive margin (R2) and low/no RAI uptake; or surgically unresectable loco-regional recurrences with low/no RAI uptake (14). The role of EBRT in the postoperative setting of DTC remains controversial in the absence of prospective randomized clinical trials (15,16).…”
Section: Discussionmentioning
confidence: 99%