EP14.06: Correlation of 3D fractional limb volumes with birthweight in fetuses with gastroschisis

Abstract

Electronic poster abstractsResults: 37 and 25 SGAs were determined using the HA and IG tables respectively. The mathematical models with HA and GI charts were able to correctly classify SGAs in 69.1% and 67.6% of cases respectively but the first one showed a greater significance (p=0.000 vs p=0.037). Conclusions:The fetal and neonatal high altitude and INTERGROWTH-21st charts were the similar capacities to predict SGA at 3400 m above sea level, but the HA charts had greater significance. Objectives: To evaluate intra-and interobserver reproducibility of third trimester ultrasound fetal measurements in normal weight and overweight pregnant women. Methods: Fetal ultrasound measurements were performed at 35weeks 0days -36weeks 6days : biparietal diameter (BPD), head circumference (HC), abdominal circumference (AC) and femur length (FL). Each measurement was evaluated twice by the first observer and a third time by a second observer that was blinded to first observer's measurements. Consensus between and among observers was analysed using the Crohnbach's α reliability coefficient (RC). We also compared intra-and interobserver measurements within subgroups -women with normal weight (body mass index < 25 Kg/m 2 ) and overweight women (body mass index ≥ 25 Kg/m 2 ) with paired sample t-test. The Bland and Altman plots were created to determine agreement and bias between paired measurements by one observer and by two observers, respectively. Results: We included 197 women, 133 with normal weight (68%) and 64 overweight (32%). For normal weight women, intra-observer α-RC for BPD, HC, AC and FL were: α=0.97; α=0.95; α=0.98 and α=0.96, respectively. Interobserver α-RC were: α =0.97; α =0.93; α=0.98 and α=0.95, respectively. For overweight women, intra-observer α -RC for BPD, HC, AC and FL were: α=0.97; α=0.93; α=0.98 and α=0.96, respectively. Interobserver α-RC were: α=0.97; α=0.94; α=0.98 and α=0.96, respectively. Intraand interobserver differences for both groups were not considered statistically significant. EP14 Conclusions:Our results demonstrate a high intra-and interobserver reproducibility of third trimester ultrasound fetal measurements, even for overweight women. Objectives: Estimated fetal weight (EFW) calculations in fetuses with gastroschisis is inherently inaccurate due to the abdominal wall defect and often yield small fetal size. The objective of this study is to compare the accuracy of 3D fractional limb volumes, specifically, thigh and arm volume percentiles versus EFW percentiles in predicting the birth weight percentiles in infants with gastroschisis to develop a more accurate birth weight calculation and improve outcome predictions. Methods: With IRB approval, a retrospective chart review of 21 fetuses with gastroschisis form October 2015 -November 2016 at a single institution was performed. Statistical analysis was performed and p<0.05 was considered statistically significant. Results: Utilising Spearman's Rho Correlation, various correlation tests were run between the following: arm volume percentile...