EP405/#363 Treatment outcome of gestational trophoblastic neoplasia patients in Bangladesh: an experience in a tertiary referral hospital

Abstract

trimester. The most common presenting complaint was vaginal bleeding (37,4%) and the commonest complication was hyperthyroidism (16,6%). Twenty-six (11,2%) patients required blood transfusion. Seventeen patients (7,2%) required a second evacuation due to ongoing bleeding with 4 patients (1,7%) requiring a hysterectomy due to excessive haemorrhage. Patients with GTD normalized their HCG at a median time of 12 weeks post evacuation. There were 40 cases of persistent trophoblastic disease (PTD), all of whom had HCG levels above 6000 mIU/mL and 4000 mIU/mL at 4 weeks and 8 weeks respectively. Almost 45% of patients never completed follow-up. Conclusions The incidence of GTD within our centre is declining but remains an important cause of morbidity as it mainly affects the reproductive age. We strongly recommend a revised follow up protocol to accommodate patients with complex socio-economic backgrounds as the current protocol seems to be associated with an increase rate of loss to follow up.