EPA-1732 – Gender transition: biological and psychosocial features of adjusting to sex reassignment - crossing literature with psychometric data from a clinical sexology unit in lisbon

Abstract

Introductiontranssexual populations seem to present specificities in brain structure, function and psychometrics, which may play an important role in adapting to the sex transition process.Objectivesto find neurobiological and psychometric features determining the adjustment to gender transition.Methodswe assessed gender identity disorder diagnosed patients of our unit clinically and through MMPI-2, and secondly, we reviewed the literature on differential brain characteristics of this population.Resultssome aspects of brain functioning may be changed by several factors, including early development and the effect of hormones in several stages of life; psychometric features may correlate with psychological adjustment and neurobiological changes, depending on psychosocial resources of the transsexual person.Conclusionsclinical protocols in gender identity disorder management may benefit from longitudinal tailoring, taking into account neurobiological and psychometric aspects, as well as their interplay.